Disrupted-in-schizophrenia 1 protein aggregates in cerebrospinal fluid are elevated in patients with first-episode psychosis.

Aim: The disrupted-in-schizophrenia 1 (DISC1) protein is a key regulator at the intersection of major signaling pathways relevant for adaptive behavior. It is prone to posttranslational changes such as misassembly and aggregation but the significance of such transformations for human mental illness has remained unclear. We aimed to demonstrate the occurrence of DISC1 protein aggregates in patients with first-episode psychosis (FEP).

The state of health of the Romany population in the Czech Republic.

The health state pilot study of Romany nationality people (432 adults and 105 children) intended on relationship between social characteristics and presentation of health problems, further on the index of absence from work due to illness and mutual relations. The frequent occurrence of diagnostic groups E10-14, F70-79 and M00-99 was found among the group of men. The results of investigation are valid in particular for our examined group.

Migration and its health and social problems in the Czech Republic. Part II.

The study follows a theoretical introduction. It tries to analyze the health and social situation of three groups of migrants: mostly ukrainian citizens, who work with Czech firms. We try to evaluate chosen methodology for further use in longitudinal following of similar groups of foreigners, who are working with Czech firms (under international contract).

Migration and its health and social problems in the Czech Republic. Part I.

Our paper considers the present situation in the care of migrants' health in the CR, its legislative aspects and attached problems as they are reported by our medical institutions. It underlines that the number of migrants in the CR is growing and that the necessity arises to create longitudinal strategic conception in their care, which would try to face social and medical problems connected with this phenomenon. Epidemiological studies carried out among the population of Europe come to the conclusion, that generally disease and injury is bigger among migrants than among the population in general.