Publications by authors named "Ruthey Vivier"
Article Synopsis
- Researchers developed small molecules that can selectively inhibit protein kinases, specifically targeting calcium-dependent protein kinase 1 (CDPK1), using a new class of photoswitchable azopyrazoles.
- These azopyrazoles enable dynamic control of CDPK1 activity by applying light of different wavelengths, allowing for fine-tuned timing in biological experiments.
- The study reveals that the effectiveness of these inhibitors is influenced by the size of the "gatekeeper" residue in CDPK1, and shows potential use against certain infections in cell cultures, paving the way for future applications in targeted kinase research.
