Publications by authors named "Ruth Rollarson"
Nucleic Acids Res
July 2022
Article Synopsis
- CRISPR gene-editing faces challenges in delivering multiple components due to the limited capacity of traditional viral vectors, which hampers genome engineering efforts.
- Researchers have utilized the high DNA cargo capacity of baculovirus to create a single viral vector that carries Cas9, sgRNA, and Donor DNAs, achieving significant success in gene editing.
- This innovative approach allows for precise delivery of genome-editing tools, including large DNA payloads and prime-editing toolkits, greatly improving the potential for effective genetic interventions in human cells.
