Accuracy and Quality Assessment of EUS-FNA: A Single-Center Large Cohort of Biopsies.

Introduction. Thorough quality control (QC) study with systemic monitoring and evaluation is crucial to optimizing the effectiveness of EUS-FNA. Methods.

Optimizing management of pancreatic cysts--prospective re-assessment for 157 cases.

Background/aims: Ongoing debate continues regarding the appropriate management of pancreatic cysts (PCs). Disagreement prevails regarding frequency of needed follow-up, if and when to perform any PC needle biopsy and indications for surgical resection. EUS is increasingly used to help determine management of PCs.

Prognostic markers in histologic and cytologic specimens of breast cancer.

Objective: To correlate histologic and cytologic specimens of breast cancer by the expression of prognostic factors, such as estrogen receptor (ER), progesterone receptor (PR) and c-erbB-2, with immunochemical staining.

Study Design: Cytologic and histologic specimens from 83 patients were analyzed for expression of ER and PR, and 30 cases were analyzed for overexpression of c-erbB-2 using a standard immunochemical method. The material used for immunocytochemical staining was taken from the needle and syringe after each aspiration and smear preparation.

Ploidy and nuclear area as a predictive factor of histologic grade in primary breast cancer.

Objective: To compare ploidy and nuclear area with histologic grade in breast cancer using cytologic samples.

Study Design: Fine needle aspirates from 85 patients with primary breast cancer were analyzed to identify ploidy and nuclear area. The Feulgen technique was used to stain the material.

Prognostic evaluation of breast cancer in cytologic specimens.

Objective: To evaluate prognostic factors in breast cancer using cytologic samples and to determine the correlation between those factors and ploidy.

Study Design: Two hundred sixteen fine needle aspirates from patients with primary breast cancer were analyzed for expression of estrogen receptors (ERs), progesterone receptors (PRs), Ki-67 antigen, expression of p53 tumor suppressor gene and overexpression of c-erbB-2 using a standard immunochemical method. Not all subjects had all biomarker information because of the study design (c-erbB2 added later).