Heme oxygenase deficiency is a rare disorder affecting heme metabolism, with only nine known cases in total.
A 3-year-old boy with this condition presented with unusual facial features, absence of the spleen, and normal bilirubin levels despite experiencing hemolysis (breakdown of red blood cells).
His treatment included blood transfusions to maintain hemoglobin levels and intravenous steroids to control inflammation.
A meta-analysis examined the effects of statin therapy on people living with HIV (PLWH), finding improvements in lipid profiles but also significant side effects that necessitate careful monitoring.*
-
The analysis included data from 12 randomized controlled trials (RCTs) involving 8,716 participants, showing notable reductions in total cholesterol, LDL, and triglyceride levels, while also noting a higher rate of treatment discontinuation compared to placebo.*
-
Overall, the benefits of statin therapy for PLWH, such as improved cholesterol levels, were found to outweigh the risks of side effects like muscle or liver issues.*