Publications by authors named "Ruth Ebenbauer"
Article Synopsis
- Carbon isotope labeling is crucial for understanding how new drugs work in the body, particularly their pharmacokinetic and pharmacodynamic properties.
- Aryl carboxylic acids are common in drugs and can be labeled using isotopically labeled carbon monoxide, but traditional methods have limitations due to excess CO and catalyst issues.
- The study introduces a new, cost-effective method using a palladium-catalyzed electrocarboxylation technique that allows for more efficient carbon-14 labeling of pharmaceuticals, enhancing drug development.
