18F-FEAU as a radiotracer for herpes simplex virus thymidine kinase gene expression: in-vitro comparison with other PET tracers.

Objective: The herpes simplex virus thymidine kinase (HSVtk) gene has frequently been applied as a reporter gene for monitoring transgene expression in animal models. In clinical gene therapy protocols, however, extremely low expression levels of the transferred gene are generally observed. Consequently, sensitive and selective radiotracers for imaging are required.

Diurnal variations of acute mountain sickness, colour vision, and plasma cortisol and ACTH at high altitude.

Time dependence of colour vision in the green/red axis, signs of acute mountain sickness (AMS), and plasma cortisol and ACTH concentrations were studied in eight sea-level male natives exposed 79 h to altitude hypoxia at 4,350 m. Colour vision (CV) was explored every 2 h from 08:00 to 20:00 hours by means of two portable anomaloscopes, one derived from Essilor CHROMOTEST and the other from the OSCAR. Significant diurnal variations in CV were found using both anomaloscopes, major alterations in green relative to red sensitivity being seen in the early morning.

Modification of colour vision in the green/red axis in acute and chronic hypoxia explored with a portable anomaloscope.

The effects of acute (4350 m), subacute (4800 m) and chronic (4800 m) altitude hypoxia on colour vision in the green/red axis were explored in eight sea-level natives by means of a simple portable anomaloscope. Subjects were required to create a yellow colour from a mixture of red (635 nm) and green (565 nm) obtained from two electroluminescent diodes. A relative decrease in green, compared to red, sensitivity was observed in each hypoxic condition (p less than 0.

A combination of amoxicillin and clavulanic acid in the treatment of respiratory tract infections caused by amoxicillin-resistant haemophilus influenzae.

This study was undertaken to evaluate the efficacy of a fixed combination of amoxicillin and clavulanic acid in 33 patients with chronic or recurrent respiratory tract infections (R.T.I.