Publications by authors named "Rutger M van Rooden"
Article Synopsis
- Abdominal Normothermic Regional Perfusion (aNRP) is a technique used before organ donation that helps evaluate organ quality during controlled donation after circulatory death (cDCD).
- A study compared pancreatic islet isolation outcomes from aNRP donors to those from cDCD and Donation after Brain Death (DBD) donors, finding that aNRP yielded significantly more islets.
- The study showed that islets from aNRP donors demonstrated good functionality, suggesting that this technique could enhance the availability and quality of pancreases for islet transplantation.
Purpose: In an effort to reduce waitlist mortality, extended criteria donor organs, including those from donation after circulatory death (DCD), are being used with increasing frequency. These donors carry an increased risk for postoperative complications, and balancing donor-recipient risks is currently based on generalized nomograms. Abdominal normothermic regional perfusion (aNRP) enables individual evaluation of DCD organs, but a gold standard to determine suitability for transplantation is lacking.
View Article and Find Full Text PDF