Publications by authors named "Rute Maria Goncalves-de-Andrade"
The genus Heinecken & Lowe, 1832 has 91 representatives in the New World. Despite medical relevancy, the taxonomy of the genus is poorly understood. South American were divided into four groups of species: , , and ; this last one has a single species, Gertsch, 1967.
View Article and Find Full Text PDFArticle Synopsis
- * Researchers identified a spider complement component homologue named Lox-FB from Loxosceles laeta, using various RNA extraction and amplification techniques.
- * Lox-FB exhibits significant similarities in structure to vertebrate and invertebrate FB/C2 proteins, featuring important domains, but lacks some conserved amino acids typically found in related proteins.
Loxoscelism is caused by envenomation by spiders from Loxosceles genus. Clinical symptoms only appear a few hours after envenomation and can evolve in local reactions, such as dermonecrosis, and systemic reactions, including intravascular haemolysis, intravascular coagulation and renal failure. Considering that alterations in the microcirculatory network are involved in the pathogenesis of different diseases, including the inflammatory process, the aim of this study was to investigate the action of venoms of males and females of Loxosceles intermedia and Loxosceles laeta on the microcirculatory network and examine the systemic production of inflammatory mediators in a murine model of loxoscelism.
View Article and Find Full Text PDFCharacterization of phenotypes of immune cells and cytokines associated with chronic exposure to Premolis semirufa caterpillar bristles extract.
PLoS One
April 2014
Article Synopsis
- - The Brazilian moth Premolis semirufa, also known as pararama, causes significant inflammatory reactions in humans and animals upon contact, leading to conditions similar to chronic synovitis.
- - A study injected mice with bristle extracts from the moth, revealing increased immune cell activity and elevated cytokine levels that indicate a strong inflammatory response.
- - The findings suggest that the immune response to pararama bristle extracts contributes to prolonged inflammation, but there is currently no effective treatment for the associated symptoms.
A new species of recluse spider, Loxosceles niedeguidonaesp. n., is described from the Parque Nacional Serra da Capivara, State of Piauí, Brazil.
View Article and Find Full Text PDFPremolis semirufa (Walker, 1856) envenomation, disease affecting rubber tappers of the Amazon: searching for caterpillar-bristles toxic components.
PLoS Negl Trop Dis
June 2012
Background: The caterpillar of the moth Premolis semirufa (Lepidoptera: Arctiidae), commonly named Pararama, is endemic of the Amazon basin. Accidental contact with these caterpillar bristles causes local symptoms such as intense heat, pain, edema and itching which last for three to seven days; however, after multiples contacts, it may induce joint-space narrowing and bone alteration, as well as degeneration of the articular cartilage and immobilization of the affected joints. Specific treatment for this disease does not exist, but corticosteroids are frequently administered.
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- Loxosceles laeta spiders were found for the first time in the West zone of São Paulo City.
- This species is significant because it's linked to loxoscelism, a serious public health issue in Southern Brazil.
- There's an urgent need to study the spider's presence in São Paulo to assess potential health risks.