Publications by authors named "Ruta Yardi"

Article Synopsis
  • Many people in rural areas in the USA have trouble getting to epilepsy specialist appointments, and this study looks into why some patients miss their appointments.
  • The study found that more people missed their in-person visits (32%) compared to telemedicine visits (20%).
  • Factors like lower income and previous missed appointments made people more likely to not show up, but using telemedicine helped more patients attend their appointments, especially those from underserved communities.
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Article Synopsis
  • The research involved 850 adults from nine international epilepsy centers, focusing on those who were seizure-free besides minor types before withdrawing medication post-surgery.
  • Predictive models were created to determine the risk of seizures returning, with key factors being certain types of seizures after surgery, prior history of specific seizures, the timing of medication withdrawal, and the number of meds taken at surgery, showing a moderate level of accuracy in predicting outcomes.
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Objective: To analyze longitudinal seizure outcomes following epilepsy surgery, including reoperations, in patients with intractable focal epilepsy.

Methods: Clinicoradiological characteristics of patients who underwent epilepsy surgery from 1995 to 2016 with follow-up of ≥1 year were reviewed. In patients undergoing reoperations, the latest resection was considered the index surgery.

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Objectives: The objective of this cohort study was to compare neuropsychological outcomes following left temporal lobe resection (TLR) in patients with epilepsy who had or had not undergone prior invasive monitoring.

Methods: Data were obtained from an institutional review board-approved, neuropsychology registry for patients who underwent epilepsy surgery at Cleveland Clinic between 1997 and 2013. A total of 176 patients (45 with and 131 without invasive EEG) met inclusion criteria.

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The purpose of this study is to look at the prevalence, characteristics, and prognostic value of somatosensory auras (SSAs) in patients who have undergone temporal lobe epilepsy (TLE) surgery to treat drug-resistant focal epilepsy. We retrospectively reviewed all patients with drug-resistant epilepsy who underwent TLE surgery at Cleveland Clinic between 2005 and 2010 (n = 333) to study the prevalence, characteristics, and prognostic implications of SSA in the context of TLE surgery. Analyses were performed using two seizure outcome definitions: complete seizure freedom and Engel classification.

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Background: Half of patients who have resective brain surgery for drug-resistant epilepsy have recurrent postoperative seizures. Although several single predictors of seizure outcome have been identified, no validated method incorporates a patient's complex clinical characteristics into an instrument to predict an individual's post-surgery seizure outcome.

Methods: We developed nomograms to predict complete freedom from seizures and Engel score of 1 (eventual freedom from seizures allowing for some initial postoperative seizures, or seizures occurring only with physiological stress such as drug withdrawal) at 2 years and 5 years after surgery on the basis of sex, seizure frequency, secondary seizure generalisation, type of surgery, pathological cause, age at epilepsy onset, age at surgery, epilepsy duration at time of surgery, and surgical side.

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Objective: We aim to develop a new scale that predicts seizure outcomes after resective epilepsy surgery.

Methods: We retrospectively reviewed patients who underwent surgery for medically refractory epilepsy at our center between 1999 and 2012. Four predictive outcome indicators were selected: preoperative seizure frequency, history of generalized tonic-clonic seizures, brain magnetic resonance imaging (MRI), and epilepsy duration.

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Objective: To study the safety of antiepileptic drug (AED) withdrawal after temporal lobe epilepsy (TLE) surgery.

Methods: We reviewed patients who underwent TLE surgery from 1995 to 2011, collecting data on doses, dates of AED initiation, reduction, and discontinuation. Predictors of seizure outcome were defined using Cox-proportional hazard modeling and adjusted for, while comparing longitudinal seizure-freedom in patients for whom AEDs were unchanged after resection as opposed to reduced or stopped.

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