Publications by authors named "Russell Manzanero"

Article Synopsis
  • The prevalence of pretreatment drug resistance (PDR) to certain HIV medications is high in Belize, particularly among those with previous treatment exposure, posing a challenge for effective antiretroviral therapy (ART).
  • WHO recommends dolutegravir-based ART regimens for their effectiveness and low resistance risk, which is crucial for reaching UNAIDS' target of 95% viral suppression.
  • Recent surveys show that while 79.6% of adults achieved viral suppression on ART, only 50% of children and adolescents did, highlighting the need for better support and adherence to treatment.
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Access to water, sanitation, and hygiene (WASH) resources in schools is critical for disease prevention and control, especially during public health emergencies. In Belize, systematic, national data on WASH in schools are needed to inform public health decisions and interventions. From December 2021 to January 2022, a national survey was sent electronically to government and government-aided primary and secondary schools in Belize (N = 308) to gather information on WASH services.

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Chagas disease is a leading cause of non-ischemic cardiomyopathy in endemic regions of Central and South America. In Belize, Triatoma dimidiata sensu lato has been identified as the predominate taxon but vectorial transmission of Chagas disease is considered to be rare in the country. We recently identified an acute case of vector-borne Chagas disease in the northern region of Belize.

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Article Synopsis
  • Existing acute febrile illness (AFI) surveillance systems can be adapted to identify new diseases like COVID-19 by testing patients who show symptoms.
  • The CDC worked with health ministries in five countries (Belize, Ethiopia, Kenya, Liberia, and Peru) to integrate COVID-19 testing into their AFI systems from March 2020 to October 2021, enrolling over 5,500 patients.
  • Testing results showed varying positivity rates for SARS-CoV-2 across countries, demonstrating that AFI surveillance can effectively enhance monitoring and response to emerging infectious diseases.
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In January 2020, we instituted acute febrile illness surveillance in 11 hospitals and clinics across Belize. Within 3 months, we diagnosed an acute case of Chagas disease by polymerase chain reaction in a 7-year-old child in the northern part of the country. Phylogenetic analyses of the parasite from the acute blood specimen revealed a multiclonal Trypanosoma cruzi infection, including parasites from the TcII (25.

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Article Synopsis
  • - WASH infrastructure and practices, particularly hand hygiene, are essential for preventing the spread of infectious diseases like COVID-19 and other respiratory illnesses, with guidance tailored to COVID-19 built upon existing WASH standards.
  • - Collaborating with local organizations, tools were created to assess WASH conditions and practices, leading to interventions aimed at mitigating COVID-19 in healthcare and community settings within low- and middle-income countries.
  • - Observations showed gaps in access to hand hygiene materials despite improved water supply, and adherence to hand hygiene was significantly better after patient contact, highlighting the need for better management of handwashing stations and enforcement of global WASH standards in communal spaces.
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The Acute Febrile Illness (AFI) Surveillance Network in Belize is a country-wide active surveillance program aimed at diagnosing vector-borne, respiratory, and enteric pathogens among patients presenting to 11 participating hospitals and clinics with new onset fever. This study describes the epidemiology of dengue virus (DENV) infections in Belize diagnosed through AFI surveillance in 2020. Of the 894 patients enrolled and PCR-tested for DENV in this period, 44 DENV-positive cases (5%) were identified.

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Worldwide, military personnel have been recognized as a population at elevated risk for sexually transmitted infections (STIs) and HIV; however, it is not well understood how the military occupation itself is implicated in the production of sexual risk behavior. Using qualitative and quantitative data collected from the Belize Defense Force (BDF), we employed a grounded theoretical framework and the Bourdieusian concept of the field and habitus to clarify how the military occupation is implicated in structuring aspects of sexual risk behaviors among personnel. We focus results on in-depth qualitative interviews conducted with 15 male-identified BDF personnel.

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Condom use during last sexual contact is a survey measure that may be used to inform monitoring and evaluation indicators of recent condom use in populations at risk for HIV infection and other sexually transmitted infections, such as the uniformed services. The authors tested for differences in condom use measures that were fielded within separate Biological and Behavioral Surveillance Surveys conducted in the armed forces of two separate nations: the Dominican Republic and Belize. Both surveys included measures of condom use during last sexual contact with specified partners and both surveys included the Risk Behavior Assessment (RBA), which measures specific sexual acts and condom use frequency during a specified time period.

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