Enhancing stability of fermented egg white gels: Influence of guar and xanthan gum addition order during yogurt-like fermentation.

Egg white gels prepared through fermentation, similar to yogurt production, offer a high-protein, zero-fat alternative to traditional dairy products. This study investigated the impact of guar gum (GG) and xanthan gum (XG) as rheological modifiers on the stability of fermented egg white gels. Rheological analysis revealed that the addition of both gums significantly influenced gel properties, with XG demonstrating superior performance.

Reducing the molecular oxygen activation energy barrier by increasing Fe-O bonds to eliminate antibiotics and their resistance genes.

Sulfamethoxazole (SMX) and its antibiotic resistance genes (ARGs) are potential threats to public health. Microwave catalytic technology is an efficient environmental remediation technology, and a reasonable design of the catalyst enables the system to achieve an ideal remediation effect under low microwave power. In this study, a microwave catalyst (FeCO-2) that activates molecular oxygen (O) was designed on the basis of rational theoretical organization.

Environmental factors ultraviolet a and ozone exacerbate the repeated inhalation toxicity of 6PPD in mice via accelerating the aging reaction.

The burden of N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine (6PPD) and its oxidized products on human health can no longer be ignored due to the detection types and concentrations in the environment continue to increase. Environmental ozone (O) and ultraviolet A (UVA) may induce ozonation and photoaging of 6PPD to produce toxic products. However, the impact of specific environmental conditions on the aging and toxic effects of 6PPD is unclear.

Multi-modal cross-domain self-supervised pre-training for fMRI and EEG fusion.

Neuroimaging techniques including functional magnetic resonance imaging (fMRI) and electroencephalogram (EEG) have shown promise in detecting functional abnormalities in various brain disorders. However, existing studies often focus on a single domain or modality, neglecting the valuable complementary information offered by multiple domains from both fMRI and EEG, which is crucial for a comprehensive representation of disorder pathology. This limitation poses a challenge in effectively leveraging the synergistic information derived from these modalities.

The effect of digital infrastructure development on household energy consumption expenditure--taking broadband China strategy as an example.

The provision of digital infrastructure and affordable energy for households is an important direction for improving the living conditions of the population. The link between digital infrastructure development and affordable energy should be examined if multiple sustainable development goals are to be achieved simultaneously for the residential sector. This study employs a staggered difference-in-differences model to investigate the effect of digital infrastructure development on household energy consumption expenditure (HECE) by using the Broadband China Strategy as an example.

Identification of neutrophil extracellular traps (NETs)-related molecular clusters in prostate cancer: Implications for predicting biochemical recurrence.

Objective: To identify neutrophil extracellular traps (NETs)-related molecular clusters and establish a novel gene signature for predicting biochemical recurrence in prostate cancer (PCa).

Methods: The transcriptome and clinicaldata of PCa sampleswere obtained from The TCGA and GEO databases. To identify NET-related molecular clusters, consensus clustering analyses were performed.

Effect of biopolymers on morphology and functionality of low-sodium condiments containing Maillard reaction products.

The impact of various biopolymers on low-sodium condiments composed of salt, potassium chloride, sodium glutamate and Maillard reaction products with chicken flavor were evaluated in order to generate uniformly distributed low-sodium condiments. The addition of biopolymers reduced the sodium and potassium content of low sodium condiments, as well as improved the particle size, changed the particle morphology. The addition of different biopolymers had different effects on the color, flow characteristics, solubility, hygroscopicity and thermal stability of low sodium condiments.

Deciphering unique enzymatic pathways in sulfonamide biotransformation by direct ammonia oxidizer Alcaligenes ammonioxydans HO-1.

Heterotrophic nitrification, similar to autotrophic nitrification, involves key enzymes and reactive nitrogen intermediates during ammonia oxidation, which may influence antibiotic transformation. However, the interference between antibiotic transformation products from ammonia oxidation and secondary metabolites in heterotrophic nitrifiers makes antibiotic transformation pathways more complicated. In this work, we observe that the heterotrophic nitrifier Alcaligenes ammonioxydans HO-1 can effectively convert sulfonamide antibiotics.

Comparison of Embolization Coils and Patent Ductus Arteriosus Occluders for Coronary Artery Fistula Transcatheter Closure: A Single Centre Experience.

Background And Objectives: There is no dedicated occlusive device for closing coronary artery fistulas (CAFs), and specific efficacy and safety data of various off-label occlusive devices for CAFs closure are scarce.

Methods: Patients undergoing transcatheter closure of CAFs from January 2011 to December 2022 were included in the single-center retrospective study. The study population was divided into 2 groups: coils group (n=35) and patent ductus arteriosus (PDA) occluders group (n=66).

LncRNA PGM5-AS1 Impairs the Resistance of Cervical Cancer to Cisplatin by Regulating the Hippo and PI3K-AKT Pathways.

Cisplatin, a platinum-based chemotherapeutic agent, can be used to treat cervical cancer (CC), but cisplatin resistance is increased during the cisplatin treatment. Long non-coding RNA PGM5-AS1 reportedly participates in CC tumorigenesis; however, its role in CC patients with cisplatin resistance has not been revealed. The present aimed to examine the role of PGM5-AS1 in modulating cisplatin resistance in CC.

Bufalin Ameliorates Myocardial Ischemia/Reperfusion Injury by Suppressing Macrophage Pyroptosis via P62 Pathway.

Bufalin, which is isolated from toad venom, exerts positive effects on hearts under pathological circumstance. We aimed to investigate the effects and mechanisms of bufalin on myocardial I/R injury. In vivo, bufalin ameliorated myocardial I/R injury, which characteristics with better ejection function, decreased infarct size and less apoptosis.

COLOR IV: a multicenter randomized clinical trial comparing intracorporeal and extracorporeal ileocolic anastomosis after laparoscopic right colectomy for colon cancer.

Introduction: Right-sided colon cancer is a prevalent malignancy. The standard surgical treatment for this condition is laparoscopic right hemicolectomy, with ileocolic anastomosis being a crucial step in the procedure. Recently, intracorporeal ileocolic anastomosis has garnered attention for its minimally invasive benefits.

Serum lipid profiling reveals characteristic lipid signatures associated with stroke in patients with leukoaraiosis.

Many lipid biomarkers of stroke have been identified, but the lipid metabolism in elderly patients with leukoaraiosis remains poorly understood. This study aims to explore lipid metabolic processes in stroke among leukoaraiosis patients, which could provide valuable insights for guiding future antithrombotic therapy. In a cohort of 215 individuals undergoing MRI, 13 stroke patients were matched with controls, and 48 stroke patients with leukoaraiosis were matched with 40 leukoaraiosis patients.

Application of mobile internet management in the continuing care of patients after radical prostatectomy.

Prostate cancer, a common malignancy in older men, often requires laparoscopic radical prostatectomy, considered the gold standard treatment. However, postoperative complications can significantly impact quality of life and psychological well-being. The emergence of mobile internet health management offers a promising approach for accessible and effective post-discharge care.

Utility of a novel scoring system for difficulty of pure laparoscopic hepatectomy for intrahepatic cholangiocarcinoma.

Despite the growing adoption of laparoscopic hepatectomy (LH) for intrahepatic cholangiocarcinoma (ICC), there is no scoring system available designed to evaluate its surgical complexity. This paper aims to introduce a novel difficulty scoring system (DSS), designated as the Wei-DSS, exclusively tailored to assess the surgical difficulty of pure LH for ICC. We retrospectively collected clinical data from ICC patients who underwent pure LH at our institution, spanning from November 2018 to May 2024.

Exploiting full-duplex opportunities in WLANs via a reinforcement learning-based medium access control protocol.

In-band full-duplex communication has the potential to double the wireless channel capacity. However, how to efficiently transform the full-duplex gain at the physical layer into network throughput improvement is still a challenge, especially in dynamic communication environments. This paper presents a reinforcement learning-based full-duplex (RLFD) medium access control (MAC) protocol for wireless local-area networks (WLANs) with full-duplex access points.

Cadmium adsorption onto aluminum hydroxide-modified attapulgite prepared with basic aluminum acetate.

Cadmium pollution in water is becoming increasingly serious. Thus, the effective removal of Cd(II) from water has garnered attention. Aluminum hydroxide-modified attapulgite (ATP-AC) was prepared from basic aluminum acetate through a coprecipitation method that could efficiently adsorb Cd(II) in aqueous solution.

Event co-occurrences for prompt-based generative event argument extraction.

Recent works have introduced prompt learning for Event Argument Extraction (EAE) since prompt-based approaches transform downstream tasks into a more consistent format with the training task of Pre-trained Language Model (PLM). This helps bridge the gap between downstream tasks and model training. However, these previous works overlooked the complex number of events and their relationships within sentences.

Plasma metabolomics profiles indicate sex differences of lipid metabolism in patients with Parkinson's disease.

The effect of sexual dimorphism on the metabolism of patients with Parkinson's disease has not been clarified. A group of patients with Parkinson's disease and healthy controls were recruited, and their clinical characteristics and plasma were collected. Untargeted liquid chromatography-mass spectrometry-based plasma metabolomics profiling was performed.

Effect of enhanced external counterpulsation versus individual shear rate therapy on the peripheral artery functions.

In this study, we aimed to assess the effects of enhanced external counterpulsation (EECP) and individual shear rate therapy (ISRT) on peripheral artery function in patients with lower extremity atherosclerotic disease (LEAD). We randomly assigned 45 LEAD patients to receive 35 sessions of 45 min of EECP (n = 15), ISRT (n = 15), or sham-control (n = 15). Flow-mediated dilation in the brachial artery (brachial-FMD); 6-min walk distance; blood flow in the popliteal, posterior tibial, anterior tibial, and dorsalis pedis arteries; and plasma levels were measured before and after the 7 weeks treatment.

Bioinformatics identifies key genes and potential therapeutic targets in the pathological mechanism of oxidative stress in Randall's plaque.

Randall's plaque (RP) is recognized as a precursor lesion for kidney stones, with its formation and progression potentially linked to oxidative stress. Previous studies have provided limited insights into the underlying mechanisms of RP, failing to fully elucidate its molecular pathways. To investigate the relationship between oxidative stress and RP, we employed bioinformatics approaches to identify key genes, predict associated pathways and drug molecules, analyze variations in immune cell populations, and construct diagnostic models.

Correlation of the weight-adjusted waist circumference index with Klotho in the United States: differences by sex.

The relationship between the weight-adjusted waist circumference index (WWI) and the senescence-inhibitory protein Klotho remains unknown. Therefore, this study aimed to investigate the relationship between WWI and soluble Klotho (s-Klotho). This study analyzed 9,928 participants based on the 2007-2016 National Health and Nutrition Examination Survey (NHANES).

Comprehensive Mass Spectral Libraries of Human Thyroid Tissues and Cells.

Thyroid nodules are a common endocrine condition with an increasing incidence over the decades. Data-independent acquisition has been widely utilized in discovery proteomics to identify disease biomarkers and therapeutic targets. To analyze the thyroid disease-related proteome in a high-throughput, reproducible and reliable manner, we introduce thyroid-specific peptide spectral libraries.

Prognostic value and immune infiltration of a tumor microenvironment-related PTPN6 in metastatic melanoma.

Background: Cutaneous melanoma is one of the most invasive and lethal skin malignant tumors. Compared to primary melanoma, metastatic melanoma (MM) presents poorer treatment outcomes and a higher mortality rate. The tumor microenvironment (TME) plays a critical role in MM progression and immunotherapy resistance.