Publications by authors named "Rushi Panchal"

Article Synopsis
  • Scientists found a way to use mice with weak immune systems to study human blood cells without making the mice sick from a disease called graft-versus-host disease (GVHD).
  • They used special antibodies that helped prevent this sickness whether injected directly into the mice or applied to the blood cells before putting them in the mice.
  • This new method makes experiments easier and cheaper, allowing researchers to learn more about blood cells faster and more efficiently.
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The objective of present work was to prepare microspheres of montelukast sodium using a natural polymer- chitosan by spray drying method by using glutaraldehyde as a cross linking agent. The microspheres were characterized for size, shape, dissolution, swelling and mucoadhesion. It was observed that, all microspheres were spherical in shape with narrow size distribution.

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The present investigation was undertaken with the objective of formulating mouth dissolving film(s) of the antiemetic drug Domperidone to enhance the convenience and compliance by the elderly and pediatric patients. Domperidone is a drug of choice in case of nausea and vomiting produced by chemotherapy, migraine headaches, food poisoning and viral infections. It causes dopamine (D2 and D3) receptor blockage both at the chemoreceptor trigger zone and at the gastric level.

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