Microstructure and Mechanical Properties of Multilayered Ti-Based Bulk Metallic Glass Composites Containing Various Thicknesses of Ti-Rich Laminates.

In order to optimize the balance between strength and toughness, a series of multilayered Ti-based bulk metallic glass composites (BMGCs) with varying thicknesses of Ti-rich layers were successfully fabricated. The findings reveal that with an increase in the thickness of the Ti-rich layers, both the flexural yield strength and ultimate strength decreased from 2066 MPa and 2717 MPa to 668 MPa and 1163 MPa, respectively. Conversely, there was a noticeable increase in flexural strain.

Radioiodination of protein using 2,3,5,6-tetrafluorophenyl 3-(nido-carboranyl) propionate (TCP) as a potential bi-functional linker: Synthesis and biodistribution in mice.

2,3,5,6-Tetrafluorophenyl 3-(nido-carboranyl) propionate (TCP), as a new potential bi-functional linker for radiohalogenation of proteins or peptides, was synthesized. With this bi-functional linker, the first attempt to conjugate bovine serum albumin (BSA) with (125)I was made and the biodistribution of the conjugated BSA ((125)I-TCP-BSA) was investigated in NIH strain mice. By the use of TCP as the linker, BSA was conjugated with (125)I in a labeling yield of 58-75% and with radiochemical purity of 99.