Publications by authors named "Rushab R Choksi"
Background: Levels of free myeloperoxidase (MPO), a cardiovascular risk marker, have been reported to decline with standard care. Whether such declines signify decreased risk of mortality remains unknown.
Design: Cox proportional hazard models were generated using data from a retrospective cohort study of prospectively collected measures.
Article Synopsis
- Many patients using statins and ezetimibe still do not meet LDL-C lowering goals, leaving them at risk for cardiovascular disease despite following recommended guidelines.
- The introduction of PCSK-9 inhibitors was a positive step in cholesterol management, but their high cost and method of administration have hindered widespread use, highlighting the need for more accessible treatments.
- Bempedoic acid, a new investigational drug, shows promise in effectively lowering LDL-C and may serve as a valuable addition to existing therapies, especially since it avoids certain side effects of statins.
Article Synopsis
- Cardiovascular disease (CVD) is a major problem for patients with type 2 diabetes (T2DM), leading to high rates of illness and death.
- Many T2DM patients are receiving treatments to prevent CVD, but significant risks still persist, especially for atherosclerotic CVD (ASCVD).
- Recent studies indicate that certain antidiabetic drugs, particularly SGLT-2 inhibitors, show promise in reducing major adverse cardiovascular events (MACE) and may offer valuable prevention strategies for CVD in different groups of patients.
Article Synopsis
- Diabetes significantly increases the risk of atherosclerotic cardiovascular disease (ASCVD), leading to serious health issues for those with diabetes.
- Effective prevention of cardiovascular complications includes managing dyslipidemia and maintaining good blood sugar control.
- New lipid-lowering therapies, especially PCSK9 inhibitors like alirocumab, show promise in helping diabetic patients achieve their cholesterol targets when traditional therapies alone are insufficient.