[Monitoring detection and treatment of new patients with pulmonary tuberculosis].

We estimated results of detection and treatment of TB patients registered in 2006 in 15 regions of RF under supervision of the Central Research Institute of Tuberculosis. The fraction of sputum positive patients increased in comparison with 2005. It ranged from 77.

[Role of material incentives of medical workers in the early detection and effective treatment of new cases of pulmonary tuberculosis in the Republic of Dagestan].

The authors studied the efficiency of material incentives in the amount of 300 rubles for each case to medical workers of the general health care network for early detection and to those of tuberculosis facilities for effective treatment us in 2001-2007. Due to the tuberculosis-controlling measures made in these years with the mechanism of material incentives to medical workers being introduced, the tuberculosis situation stabilized and the major epidemiological indices, such as morbidity, mortality, and prevalence, decreased by 1.3, 2.

[Monitoring of the detection of new pulmonary tuberculosis cases and the efficiency of their treatment in the area supervised by the Central Research Institute of Tuberculosis, Russian Academy of Medical Sciences].

The results of the detection and treatment of new pulmonary tuberculosis cases in 2006 were assessed in 15 subjects of the Russian Federation, supervised by the Central Research Institute of Tuberculosis, Russian Academy of Medical Sciences. As compared with 2005, in 2006 the proportion of bacteria-discharging individuals increased among the new cases of pulmonary tuberculosis and ranged from 77.1% in the Oryol Region to 35.

[Individual approaches to complex treatment of disseminated tuberculous processes in adolescents].

Complex treatment including an individual selection of chemotherapy regimens with their timely correction and various laser therapy modalities was used in 147 adolescents with a first detected disseminated pulmonary tuberculous process (DPTP). All the patients were initially given treatment regimen 1. According to the results of chemotherapy correction (adverse reactions to antituberculous agents and drug resistance of Mycobacterium tuberculosis), the patients were divided into 3 groups.

[Pulmonary tuberculosis in adolescents in relation to different degree of drug resistance].

Ninety adolescents with bacterial isolates of active forms of pulmonary tuberculosis were followed up. Drug resistance of Mycobacteria tuberculosis was revealed in 57 (63.3%) patients.

[Efficiency of supra-venous blood laser radiation used in the treatment of disseminated pulmonary tuberculosis in adolescents].

In 19 of 40 adolescent patients with disseminated pulmonary tuberculosis, supravenous blood laser radiation was used in the complex treatment 2-3 weeks after the initiation of chemotherapy. The use of this type of laser therapy enhanced the efficiency of the treatment, accelerated positive changes of tuberculosis by 2.5-3.

[Modern aspects of the combined treatment of pulmonary tuberculosis in adolescents].

The paper presents the follow-up data on 171 adolescents with active pulmonary tuberculosis. Extensive, complicated processes were encountered in 30% of patients. Chemotherapy was used in relation to the severity of disease, to the presence of decay and bacterial isolation, to the sensitivity of Mycobacteria tuberculosis.

[Organizational-methodological approaches to treating tuberculosis in children and adolescents in the growth of an endemic disease].

The paper presents guidelines in treating tuberculosis in children from the experience gained in Russia and other foreign countries. Emphasis is laid on the necessity of applying a comprehensive approach to the treatment whose main constituents are sanitary and dietary regimens, etiotropic and pathogenetic therapies, prevention of exacerbations or treatment of concomitant diseases. It is important to use antituberculous agents rationally by determining a standard treatment regimens for patients with various somatic diseases.

[Rapidly progressing forms of pulmonary tuberculosis in adolescents].

Examination of 23 adolescents with rapidly progressive pulmonary tuberculosis (RPPT) discovered severe bilateral lesions in 47.8%, caverns in 91.3%, M.

[Approaches to combined therapy of pulmonary tuberculosis in adolescents excreting drug-resistant Mycobacterium tuberculosis].

The data are presented on 138 adolescents with active, advanced tuberculosis. M. tuberculosis were detected in the sputum and bronchial lavage of 75(54.

[Carbohydrate metabolism impairment and specific features of the course of tuberculosis in adolescents with diabetes mellitus].

The paper deals with the detection of carbohydrate metabolic disturbances in adolescents with tuberculosis and analyzes their impact on the course of a specific process. Borderline carbohydrate metabolic disorders were identified in 10.8% of the 130 patients examined.

[Magnetic laser therapy in combination with lymphotropic drugs administration in treating teenagers with common forms of tuberculosis].

The paper shows the efficiency of combined use of magnetic laser therapy (MLT) and lymphotropic drug therapy in 40 teenagers with common forms of tuberculosis. The use of laser makes it possible to modify methods of regional lymphotropic therapy, to prolong its use and increase indications for it. MLT in combination with lymphotropic drug therapy accelerates positive changes and hence enhances the efficiency of tuberculosis treatment.

[Intravenous laser radiation treatment of acute and progressive forms of tuberculosis in teenagers].

In 25 of 44 teenagers suffering from acute and progressive tuberculosis, intravenous blood laser radiation was included into its multimodality treatment following 2-4 weeks of the initiation of chemotherapy. The use of laser enhanced the efficiency of treatment, accelerated positive changes by 1.5-2 months by major clinical and laboratory indices, made the disease run smoothly and caused less pronounced residual changes in the lung.

[Effectiveness of immunodiagnosis of drug intolerance in adolescents having tuberculosis and concomitant diseases].

Fifty seven adolescents having tuberculosis and clinical signs of drug intolerance were examined by immunological tests (thermistometry and blast-transformation reaction in 20 and 37 patients, respectively). Of them 30 patients had concomitant diseases. Patients with concurrent abnormalities require laboratory evidence for drug intolerance.

[The diagnostic value of serological studies in the clinical picture of tuberculosis].

Circulating antituberculous antibodies in the sera from 89 patients with pulmonary tuberculosis and 11 patients with tumors and nonspecific inflammation in the lungs were evaluated using indirect hemagglutination and enzyme immunoassay. Specific antibodies were detected in 81.6 and 30% of tuberculous and nontuberculous patients, respectively.

[Anthelmintic therapy of opisthorchiasis in patients with active tuberculosis].

Study was based on the clinical and laboratory follow up of 34 patients with active pulmonary tuberculosis in 12 of whom it was concurrent with opisthorchiasis. The clinical course of the combined pathology and immunopathogenesis were evaluated by the monocytic interleukin-1 capacity to regulate the immune T-system status. In conditions when the course of tuberculosis is aggravated by opisthorchiasis invasion, the number of cases of antibacterial therapy intolerance increases and prognosis of the diseases deteriorates, it is expedient to use the anthelminthic therapy with a new preparation biltricide which also has an immunomodulating action.

[Experimental substantiation of MPEL of dibenz(a,n)anthracene in atmospheric air].

Overt dependence of lung tumour development on the values of the dose administered was shown in experiments on inbred white rats under intratracheal administration of various doses of dibenz (a, h) anthracene (DBA); minimal-effect dose and maximal no-effect dose of DBA were established in the experiment. A theoretically calculated allowable dose was used to calculate MAC of the chemical under study for the ambient air 5 ng/m3 was recommended as an average 24-hour maximum allowable concentration of DBA in ambient air.