Publications by authors named "Rupali Aggarwal"

Leiomyosarcomas of vascular origin are uncommon. They arise from the smooth muscles of tunica media of major blood vessels. Most of the cases are present in women.

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Purpose: Triple-negative breast cancer (TNBC) is a heterogeneous group of tumors comprising various breast cancers simply defined by the absence of estrogen receptor, progesterone receptor and overexpression of human epidermal growth factor receptor 2 gene. In this review, we discuss the epidemiology, risk factors, clinical characteristics and prognostic variables of TNBC, and present the summary of recommended treatment strategies and all other available treatment options.

Methods: We performed a systematic literature search using Medline and selected those articles which seemed relevant for this review.

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Aims: We present retrospective analysis of patients of glioblastoma multiforme (GBM) and discuss clinical characteristics, various treatment protocols, survival outcomes, and prognostic factors influencing survival.

Materials And Methods: From January 2002 to June 2009, 439 patients of GBM were registered in our department. The median age of patients was 50 years, 66.

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Purpose: To evaluate the role of high-dose-rate intraluminal brachytherapy (ILBT) through percutaneous transhepatic biliary drainage (PTBD) in patients with malignant biliary obstruction, in terms of improvement in symptoms, quality of life (QOL), and survival.

Methods And Materials: From August 2004 to October 2006, 18 patients aged 30-70 years, who were found unsuitable for surgical resection or were inoperable because of poor general condition, were taken up for palliative ILBT through PTBD. All patients underwent PTBD followed by internal-external drainage.

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Brain metastasis is common in patients with non-small-cell lung carcinoma (NSCLC) and is associated with poor prognosis with a median survival rate below six months, even if treated with palliative radiotherapy and/or chemotherapy. Here, we report a case of NSCLC with synchronous brain metastasis treated with whole brain radiotherapy, systemic chemotherapy and oral gefitinib with survival of 62 months. We found that adequate treatment combining radiotherapy, chemotherapy and targeted therapy in a patient with non-small-cell lung cancer with brain metastasis can improve survival.

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