Publications by authors named "Rupak Banerjee"

MoS quantum dots (MQDs) with an average size of 1.9 ± 0.7 nm were synthesized using a microwave-assisted method.

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Background: Evaluating the severity of aortic stenosis (AS) can be challenging, particularly in patients with low-gradient (LG, Δp < 40 mmHg) AS.

Objective: This study aims to improve the accuracy of assessing severity of AS using a novel functional index- Aortic Valve Coefficient (AVC). The AVC is defined as ratio of mean transvalvular pressure-drop (Δp) to the proximal dynamic pressure (1/2 × blood density × V; V: left ventricular outflow tract peak velocity).

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Investigating the influence of different cellular mechanical and physical properties on cells in vitro is important for assessing cellular activities like differentiation, proliferation, and migration. Evaluating the mechanical response of the cells lodged on a scaffold due to variations in substrate roughness, substrate elasticity, fluid flow, and the shapes of the cells is the main goal of the study. In this comprehensive analysis, a combination of the fluid structure interaction method and the submodeled finite element technique was employed to anticipate the mechanical responses across various cells at the interface between cells and the substrate.

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Article Synopsis
  • The hyperaemic stenosis resistance (HSR) index is a new measure that combines pressure drop and blood flow to provide a better assessment of coronary artery disease severity compared to traditional methods like fractional flow reserve (FFR) and coronary flow reserve (CFR).
  • This study analyzed data from 853 patients with chronic coronary syndromes to evaluate HSR's diagnostic and prognostic value, finding it to more accurately identify inducible ischaemia and predict long-term target vessel failure.
  • The results suggest HSR can help determine which obstructed vessels may benefit from treatment, reinforcing its potential as a superior tool in clinical practice for managing coronary artery disease.
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Immunoassays based on reactions between target pathogen (antigen; Ag) and antibody (Ab) are frequently used for Ag detection. An external magnetic field was used to immobilize magnetic microbeads-tagged-antibodies (mMB-Ab) on the surface of a microchannel in the capture zone. The mMB-Ab was subsequently used for Ag detection.

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We present a facile and versatile strategy for enabling CsPbI rods to self-assemble at an air-water interface. The CsPbI rods, which float at the air-water interface, align under the influence of the rotational flow field due to the vortex motion of a water subphase. The aligned CsPbI rods could be transferred onto various substrates without involving any sophisticated instrumentation.

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Article Synopsis
  • The microvascular resistance reserve (MRR) is a new index used to evaluate how well the coronary circulation can dilate, particularly in patients with coronary artery disease (CAD), and its assessment may require special considerations for women.
  • This study aimed to evaluate how effective the MRR is for diagnosis and prognosis in women compared to men, using data from the ILIAS Registry.
  • Results showed that MRR is a significant predictor of major adverse cardiac events (MACE) for both sexes, with similar correlations and cut-off values for predicting outcomes in women and men.
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Article Synopsis
  • This study evaluates the prognostic value of coronary pressure and flow parameters in patients who did not undergo revascularization due to borderline readings.
  • It included 1,971 blood vessels, and found that abnormal pressure and flow metrics significantly predicted long-term risks of target vessel failure (TVF), myocardial infarction (MI), and cardiac death over five years.
  • The study concluded that both resting and hyperemic conditions are important independent factors in predicting cardiac events, with their abnormal flow readings providing additional prognostic information.
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Article Synopsis
  • Microvascular resistance (MR) is important in assessing patient outcomes after coronary procedures, but its changes and links to target vessel failure (TVF) haven’t been thoroughly studied before.
  • This research analyzed data from the ILIAS registry, focusing on the relationship between MR changes and TVF outcomes in post-percutaneous coronary intervention (PCI) patients, involving 295 vessels from 828 patients.
  • Findings showed that an increase in MR post-PCI was linked to higher rates of TVF, indicating that patients with less severe baseline conditions might have worse outcomes if MR increases after the procedure.
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Background And Aims: The management of chronic coronary syndrome (CCS) is informed by studies predominantly including men. This study investigated the relationship between patients sex and different endotypes of CCS, including sex-specific clinical outcomes.

Methods: In patients with CCS undergoing coronary angiography, invasive Fractional Flow Reserve (FFR) and Coronary Flow Reserve (CFR) were measured.

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The main challenges impeding the widespread use of organic-inorganic lead halide perovskites in modern-day technological devices are their long-term instability and lead contamination. Among other environmentally convivial and sustainable alternatives, CsSnX (X = Cl, Br, and I) compounds have shown promise as ambient-stable, lead-free materials for energy harvesting, and optoelectronic applications. Additionally, they have demonstrated tremendous potential for the fabrication of self-powered nanogenerators in conjunction with piezoelectric polymers like polyvinylidene-fluoride (PVDF).

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Lead-free halide perovskites have gained immense popularity in photovoltaic and energy harvesting applications because of their excellent optical and electrical attributes with minimal toxicity. We synthesized composite films of lead-free CsBiBr perovskite embedded in the polyvinylidene fluoride (PVDF) matrix and have investigated their piezoelectric energy harvesting. Five PVDF@CsBiBr composite films were fabricated with varying wt% of the perovskite in the PVDF.

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Article Synopsis
  • The study focuses on the microvascular resistance reserve (MRR) as a way to evaluate the vasodilator capacity of the coronary microcirculation while considering the effects of epicardial disease.
  • It involved 1,481 patients and found a good correlation between MRR and coronary flow reserve (CFR), indicating MRR’s potential as a reliable measure.
  • MRR was associated with major adverse cardiac events (MACE) and target vessel failure (TVF) over five years, suggesting it could be a better diagnostic tool than other measures in patients with significant epicardial coronary artery disease.
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Emergency medical service (EMS) providers have a higher potential exposure to infectious agents than the general public (Nguyen et al., 2020, "Risk of COVID-19 Among Frontline Healthcare Workers and the General Community: A Prospective Cohort Study," Lancet Pub. Health, (9), pp.

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The prognostic value of abnormal resting Pd/Pa and coronary flow reserve (CFR) after fractional flow reserve (FFR)-guided revascularisation deferral according to sex remains unknown. From the ILIAS Registry composed of 20 hospitals globally from 7 countries, patients with deferred lesions following FFR assessment (FFR > 0.8) were included.

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Objective: The aim of this study is to evaluate the diagnostic and prognostic value of non-hyperaemic Pd/Pa and to determine its additional value when combined with the gold standard hyperaemic pressure ratio (FFR) to guide revascularization.

Methods: In a large, multi-center, retrospective registry, we included a total of 2141 patients with a clinical indication for coronary angiography providing physiological data in 2726 vessels. A classification was made based on the FFR (cut-off value: 0.

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Background Intracoronary physiologic indexes such as coronary flow reserve (CFR) and left ventricular ejection fraction (LVEF) have been regarded as prognostic indicators in patients with coronary artery disease. The current study evaluated the association between intracoronary physiologic indexes and LVEF and their differential prognostic implications in patients with coronary artery disease. Methods and Results A total of 1889 patients with 2492 vessels with available CFR and LVEF were selected from an international multicenter prospective registry.

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Background: Coronary microvascular dysfunction (CMD) is an important contributor to angina syndromes. Recently, two distinct endotypes were identified using combined assessment of coronary flow reserve (CFR) and minimal microvascular resistance (MR), termed structural and functional CMD.

Aims: We aimed to assess the relevance of the combined assessment of CFR and MR in patients with angina and no obstructive coronary arteries.

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Background: Coronary pressure indices such as fractional flow reserve are the standard for guiding elective revascularization. However, considering additional coronary flow parameters could further individualize and optimize the decision on revascularization. We aimed to investigate the potentially differential prognostic associations of elective percutaneous coronary intervention (PCI) according to coronary flow properties represented by coronary flow reserve (CFR), coronary flow capacity (CFC), and baseline CFC (bCFC).

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Objectives: The aim of this study was to demonstrate the clinical implications of combined assessment of fractional flow reserve (FFR) and coronary flow reserve (CFR).

Background: Combined assessment of FFR and CFR allows detailed characterization of pathophysiology in chronic coronary syndromes. Data on the clinical implications of distinct FFR and CFR patterns are limited, leading to uncertainty regarding their relevance.

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Objectives: The authors sought to evaluate comparative prognosis between deferred versus performed percutaneous coronary intervention (PCI) according to coronary flow reserve (CFR) values of patients with intermediate fractional flow reserve (FFR).

Background: For coronary stenosis with intermediate FFR, the prognostic value of PCI remains controversial. The prognostic impact of PCI may be different according to CFR in patients with intermediate FFR.

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Background In the absence of obstructive coronary stenoses, abnormality of noninvasive stress tests (NIT) in patients with chronic coronary syndromes may indicate myocardial ischemia of nonobstructive coronary arteries (INOCA). The differential prognosis of INOCA according to the presence of coronary microvascular dysfunction (CMD) and incremental prognostic value of CMD with intracoronary physiologic assessment on top of NIT information remains unknown. Methods and Results From the international multicenter registry of intracoronary physiologic assessment (ILIAS [Inclusive Invasive Physiological Assessment in Angina Syndromes] registry, N=2322), stable patients with NIT and nonobstructive coronary stenoses with fractional flow reserve >0.

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Two dimensional (2D) CsPbBrhave been successfully synthesized via the chemical precipitation method. Detailed structural, morphological, optical, and dielectric studies of these materials have been performed. These 2D CsPbBrplates (of thickness around 200-300 nm) are ascribed to a tetragonal lattice system with4/space group.

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The present research investigates the pharmacokinetics and toxicity of a chitosan (CS) and poly(lactic-co-glycolic) acid (PLGA)-based methotrexate (MTX) intravitreal micro-implant in normal rabbit eyes. PLGA and CS-based micro-implants containing 400 µg of MTX were surgically inserted in the vitreous of twenty-four New Zealand rabbits using minimally invasive procedures. The PLGA-coated CS-MTX micro-implant and the placebo micro-implant were inserted in the right eye and in the left eye, respectively, of each rabbit.

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A close-packed monolayer of a two-dimensional periodic array of Silica nanospheres (SNs) with gold (Au) crowning, forming a long-ranged archetypal plasmonic-photonic nanocomposite, has been achieved. We investigate the thermal crowning mechanism in such a nanocomposite using electron microscopy and X-ray diffraction techniques. Pre- and post-annealing morphological features reveal gold crowning on top of SNs, at different annealing temperatures for various thicknesses of the sputter-deposited gold.

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