Publications by authors named "Ruoyu Dang"

Article Synopsis
  • Helicobacter pylori (H. pylori) is increasingly resistant to antibiotics globally, complicating treatment efforts for infections.
  • A new whole genome sequencing (WGS) assay was developed to analyze 73 H. pylori strains from patients in Tianjin, China, linking specific genetic mutations to antibiotic resistance.
  • Four super-resistant strains were identified that formed biofilms, indicating that biofilm formation is another mechanism of resistance, suggesting that biofilm-related genes could be valuable for resistance screening.
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Objective: The aim of this study was to identify hub genes associated with immune cell infiltration in breast cancer through bioinformatic analyses of multiple datasets.

Methods: Nonparametric (NOISeq) and robust rank aggregation-ranked parametric (EdgeR) methods were used to assess robust differentially expressed genes across multiple datasets. Protein-protein interaction network, GO, KEGG enrichment, and sub-network analyses were performed to identify immune-associated hub genes in breast cancer.

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Coronary artery disease (CAD) exerts a global challenge to public health. Genetic heritability is one of the most vital contributing factors in the pathophysiology of CAD. Co-expression network analysis is an applicable and robust method for the interpretation of biological interaction from microarray data.

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Macrophages enhance glioma development and progression by shaping the tumor microenvironment. Class A1 scavenger receptor (SR-A1), a pattern recognition receptor primarily expressed in macrophages, is up-regulated in many human solid tumors. We found that SR-A1 expression in 136 human gliomas was positively correlated with tumor grade (P<0.

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