Butyrate attenuates cold-induced hypertension via gut microbiota and activation of brown adipose tissue.

Objective: Chronic exposure to cold temperature is known to elevate blood pressure, leading to a condition known as cold-induced hypertension (CIH). Our previous research suggested correlations between alterations in gut microbiota, decrease in butyrate level, and the onset and progression of CIH. However, the role of butyrate in CIH and the underlying mechanisms need further investigation.

Residential greenspace and blood lipids in an essential hypertension population: Mediation through PM and chemical constituents.

Fine particulate matter (PM) adversely affects blood lipids, while residential greenspace exposure may improve blood lipids levels. However, the association between exposure to residential greenspace and blood lipids has not been adequately studied, especially in vulnerable populations (e.g.

Associations of PM composition and green space with metabolic syndrome in a Chinese essential hypertensive population.

Background: Metabolic syndrome (MetS) has emerged as a significant global public health concern. While environmental factors, including PM, have been identified as important risk factors for MetS in the general population, limited studies have investigated their impact on individuals with essential hypertension. Therefore, our study aims to explore the relationship between PM composition, green space, and their combined effects on MetS among a Chinese essential hypertensive population.

Association between salt sensitivity of blood pressure and the risk of hypertension in a Chinese Tibetan population.

Epidemiological studies have confirmed salt sensitivity as a crucial risk factor for the development of hypertension. However, few studies have investigated the association between salt sensitivity of blood pressure (SSBP) and hypertension in Chinese Tibetan population. Therefore, we conducted a cross-sectional study based on a Tibetan population to evaluate the association between SSBP and the risk of hypertension.

The association between endocrine disrupting chemicals and MAFLD: Evidence from NHANES survey.

Previous studies on the association of endocrine-disrupting chemicals (EDCs) with metabolic dysfunction-associated fatty liver disease (MAFLD) are very limited. This study analyzed the association of EDCs exposure with MAFLD among 5073 American adults from the 2017-2018 National Health and Nutrition Examination Survey. The results showed that increased exposure to 3 EDCs metabolites (namely As, DiNP and PFOA) were significantly associated with MAFLD, the odds ratio of which were 1.

The Interactive Effects between Drought and Air Pollutants on Children's Upper Respiratory Tract Infection: A Time-Series Analysis in Gansu, China.

As a destructive and economic disaster in the world, drought shows an increasing trend under the continuous global climate change and adverse health effects have been reported. The interactive effects between drought and air pollutants, which may also be harmful to respiratory systems, remain to be discussed. We built the generalized additive model (GAM) and distributed lag nonlinear model (DLNM) to estimate the effects of drought and air pollutants on daily upper respiratory infections (URTI) outpatient visits among children under 6 in three cities of Gansu province.

Seasonal characteristics of ambient temperature variation (DTR, TCN, and TV) and air pollutants on childhood asthma attack in a dry and cold city in China.

Very few researches have concentrated on a variety of time scales to evaluate the association between temperature variation (TV) and childhood asthma (CA), and the evidence for the interaction of air pollutants on this association is lacking. In this study, we aim to estimate the relative risks (RRs) of CA due to TV by following metrics: diurnal temperature range (DTR), temperature changes between neighboring days (TCN), and temperature variability (TV); to quantify the seasonal attributable fraction (AF) and number (AN) of CA due to TV; to examine the interactive effects of the TV and air pollutants on CA in different seasons. We mainly applied distributed lagged nonlinear model (DLNM) and conditional Poisson models to evaluate the associations between TV and outpatient visits for CA during 2014-2019 in Lanzhou, China.

Mixed heavy metals exposure affects the renal function mediated by 8-OHG: A cross-sectional study in rural residents of China.

Heavy metals are important risk factors for kidney, but their co-exposure effect on kidney and related mechanism remain unclear. This study evaluated the relationship between heavy metals and renal function, and the feasible mediation effect of oxidative stress. Based on the Dongdagou-Xinglong cohort, participants were recruited and their information were collected through questionnaires and physical examinations.

Perchlorate, nitrate, and thiocyanate and depression: the potential mediating role of sleep.

Perchlorate, nitrate, and thiocyanate are common thyroid disruptors, but it is not clear whether they are related to depression. In this study, we aimed to investigate the association between perchlorate, nitrate, and thiocyanate and depression, and to explore the potential role of sleep in this process. We used data from the National Health and Nutrition Examination Survey (NHANES).

The Effects of Short-Term PM Exposure on Pulmonary Function among Children with Asthma-A Panel Study in Shanghai, China.

Fine particulate matter (PM) has been reported to be an important risk factor for asthma. This study was designed to evaluate the relationship between PM and lung function among children with asthma in Shanghai, China. From 2016 to 2019, a total of 70 Chinese children aged 4 to 14 in Shanghai were recruited for this panel study.

Effects of long-term exposure to PM and chemical constituents on blood lipids in an essential hypertensive population: A multi-city study in China.

Previous studies on the effects of fine particulate matter (PM) and chemical constituents on lipid disorder among hypertension populations, particularly in China, are very limited. We aimed to examine the effects of long-term exposure to PM and chemical constituents on dyslipidemias in China. Finally, we included 34,841 participants with essential hypertension from 19 regions in China during 2010-2011.

Cold exposure, gut microbiota, and hypertension: A mechanistic study.

Cold exposure has been recognized as an important risk factor for hypertension, and altered gut microbiota has been reported to be associated with hypertension. We hypothesized that there is a plausible relationship between gut microbiota and cold-induced hypertension (CIH). Therefore, we explored the potential link between the gut microbiota and its metabolites with CIH.

Physical activity reduces the role of blood cadmium on depression: A cross-sectional analysis with NHANES data.

Cadmium (Cd) exposure is recognized as an important risk factor for psychological health, but suitable physical activity may relieve depression. However, it remains unknown whether physical activity (PA) can reduce the effect of cadmium exposure on depression. Therefore, a cross-sectional data from National Health and Nutrition Examination Survey (NHANES) 2015-2018 was used.

Effects and Interaction of Meteorological Parameters on Influenza Incidence During 2010-2019 in Lanzhou, China.

Background: Influenza is a seasonal infectious disease, and meteorological parameters critically influence the incidence of influenza. However, the meteorological parameters linked to influenza occurrence in semi-arid areas are not studied in detail. This study aimed to clarify the impact of meteorological parameters on influenza incidence during 2010-2019 in Lanzhou.

Indoor solid fuel use and renal function among middle-aged and older adults: A national study in rural China.

Solid fuel use is the main source of indoor air pollution, especially in rural areas of developing countries. Nevertheless, the evidence linking indoor solid fuel use and renal function is very limited. Therefore, we investigated the association between indoor solid fuel use and renal function among middle-aged and older adults in rural China.