Rare rectal gastrointestinal stromal tumor case: A case report and review of the literature.

Background: Gastrointestinal stromal tumors (GISTs) are rare tumors of the gastrointestinal tract accounting for less than 1% of all gut tumors. GISTs occurring in the rectum are extremely rare, and these usually present at an advanced stage compared with other sites.

Case Summary: A 60-year-old male who presented with features of sensations of rectal tenesmus was referred to our department with a mass in the lower rectum that was detected during a routine checkup.

Mechanism Exploration of Environmental Pollutants on Premature Ovarian Insufficiency: a Systematic Review and Meta-analysis.

As a public health problem, premature ovarian insufficiency leads to infertility or sub-fertility. In addition to premature ovarian insufficiency (POI) increases the lifetime risk of bone fragility, cardiovascular disease, and cognitive impairment. To investigate the effects of environmental pollutants on the occurrence of POI and explore its mechanism, we conducted a computer search for articles published in electronic databases by December 13, 2022.

Establishment of a mouse model of inflammatory bowel disease using dextran sulfate sodium.

Background: Dextran sulfate sodium (DSS)-induced murine colitis is the most commonly used model for the analysis of the pathogenesis of inflammatory bowel disease (IBD) and for the assessment of the efficacy of putative therapeutics. It has been suggested that mice should be given 2.5-10% DSS for 3-7 days to establish the model.

Investigating the association between anxiety symptoms and mood disorder in high-risk offspring of bipolar parents: a comparison of Joint and Cox models.

Background: Anxiety is associated with mood disorders including bipolar disorder. Two statistical modelling frameworks were compared to investigate the longitudinal relationship between repeatedly measured anxiety symptoms and the onset of depression and bipolar disorder in youth at confirmed familial risk.

Methods: Prospectively collected data on 156 offspring of a parent with confirmed bipolar disorder participating in the Canadian Flourish high-risk offspring longitudinal cohort study were used for this analysis.

Investigation of return photons from sodium laser beacon excited by a 40-watt facility-class pulsed laser for adaptive optical telescope applications.

The brightness of the artificial beacon is one critical performance parameter for adaptive optics. Here, a 40-watt level narrow-linewidth microsecond pulsed yellow laser is produced at 589 nm with a high repetition frequency of 600 Hz and a pulse duration of 120 μs. An experiment to project the pulse beam up to the sky and measure the fluorescence photon returns of the Na atoms has been held on the 1.