Fluorescence-enhanced supra-amphiphiles based on pillar[5]arene: construction, controllable self-assembly and application in cell imaging.

Fluorescence-enhanced supra-amphiphiles based on (WP5)⊃ENDTn were constructed successfully. When = 9, they can self-assemble into uniform micelles with an average diameter of about 90 nm and be further applied in cell imaging.

Polydopamine modified by pillar[5]arene for targeted chemo-photothermal cancer therapy.

A pillar[5]arene-modified polydopamine (PDA-P[5]OH) displaying pH/NIR dual-responsive properties was constructed successfully for targeted chemo-photothermal cancer therapy.

Emissive Nanoparticles from Co-assembly of Metallatetragon and Amphiphilic Tetraphenylethylene for Cancer Theranostics.

Platinum(II)-based metallacycles/cages have obtained tremendous attention due to their fascinating topology and wide range of applications, such as fluorescent materials, cell imaging, and tumor treatment. In this work, a metallatetragon () was constructed from 4-(4-(1,2,2-triphenylvinyl)phenyl)pyridine () and 90° -Pt(II) () in acetone through the strategy called "coordination driven self-assembly". Interestingly, through co-assembly of and poly(ethylene glycol)-modified tetraphenylethylene (), fluorescent nanotheranostics, which could generate singlet oxygen (O) under the NIR irradiation and release Pt drugs under a low-pH microenvironment, were prepared successfully.

Pillar[5]arene-Derived Terpyridinepalladium(II) Complex: Synthesis, Characterization, and Application in Green Catalysis.

Metal nanoparticle catalysts have attracted great interest because they possess high surface-to-volume ratios and exhibit a very large number of catalytically active sites per unit area. However, high surface-to-volume ratios will induce nanoparticle aggregates during the catalytic reactions, making them lose their catalytic activity. In this work, a monoterpyridine-unit-functionalized pillar[5]arene (TP5) was synthesized successfully, which can be used as anchoring sites for the controllable preparation of well-dispersed palladium nanoparticles [TP5/Pd(0) NPs].

Pillar[5]arene-based [1]rotaxanes with salicylaldimine as the stopper: synthesis, characterization and application in the fluorescence turn-on sensing of Zn in water.

Two pillar[5]arene-based [1]rotaxanes with salicylaldimine as the stopper were synthesized and characterized fully, and could be further applied in the fluorescence turn-on sensing of Zn in water.

Platinum(II)-Metallaclip-Based Theranostics for Cell Imaging and Synergetic Chemotherapy-Photodynamic Therapy.

Supramolecular coordination complexes formed by coordination-induced assembly not only avoid the loss of activity of precursors but also provide an efficient way for controlled release, which can be further used in various fields of biology such as drug delivery, cell imaging, and tumor treatment. In this work, a Pt metallaclip () was prepared from 4-[4-(1,2,2-triphenylvinyl)phenyl]pyridine (), 5,10,15-triphenyl-20-(pyridin-4-yl)porphyrin (), , and glycol-chain-modified isophthalic acid () in an acetone/water mixture through the "coordination-driven self-assembly" method. P and H NMR spectroscopy and high-resolution mass spectrometry were used to characterize the obtained metallaclip .

Activation of Topological Defects Induces a Brittle-to-Ductile Transition in Epithelial Monolayers.

Epithelial monolayers are subjected to various mechanical forces, such as stretching, shearing, and compression. Thus, its mechanical response to external loadings is essential for its biological functions. However, the mechanism of the fracture failure of the epithelial monolayer remains poorly understood.