Publications by authors named "Ruoshu Duan"
Metastatic hepatocellular carcinoma (HCC) seriously threatens patients' prognosis. It was previously suggested that the insulin growth factor binding protein (IGFBP) family could serve as cancer suppressors in the development and metastasis of HCC. However, the role of IGFBP4 and its underlying molecular mechanism in HCC metastasis is elusive.
View Article and Find Full Text PDFTo investigate the association of demographic, clinical, and metabolic factors with nonalcoholic fatty liver disease (NAFLD) in a non-overweight/obese and overweight/obese Chinese population at risk for metabolic syndrome. A cross-sectional multicenter study was conducted using convenience sampling from eight selected counties/cities in Zhejiang, China, between May 2021 and September 2022. Demographics, epidemiological, anthropometric, and clinical characteristics were obtained from a questionnaire.
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- * The study used gene expression data to analyze differentially expressed genes related to heart failure, leading to the identification of core genes and their connection to oxidative stress and immune responses.
- * Key findings included six gene modules, with ECM2, METTL7B, MNS1, and SFRP4 identified as significant signature genes for heart failure, which may also have implications for lung cancer.
Article Synopsis
- This study evaluated malnutrition using GLIM criteria and SGA in outpatients experiencing unintentional weight loss (UWL), focusing on predicting unplanned hospitalizations.
- The analysis involved 257 adult participants over two years, finding a high prevalence of malnutrition (79% by GLIM, 72% by SGA) and demonstrated good agreement between the two assessment methods.
- Key findings revealed that GLIM-defined malnutrition significantly increased the risk of unplanned hospital admissions, with disease burden or inflammation being the strongest predictor among the GLIM criteria.