Interaction between and gene polymorphisms with susceptibility to ischemic stroke in Chinese population.

Unlabelled: The objective of this study was to test the relationship of several single nucleotide polymorphisms (SNPs) within phosphodiesterase 4D () and connexin 37 () gene additional interactions with ischemic stroke (IS) risk. The online software SNPstats was used for Hardy–Weinberg equilibrium testing. Generalized multifactor dimensionality reduction (GMDR) was employed to detect the potential interactions among gene, ene, and smoking.