MicroRNAs(miRNAs) are promising biomarkers for early esophageal squamous cell carcinoma (ESCC) detection and prognostic prediction. This study aimed to explore the potential biomarkers and molecular pathogenesis in the early diagnosis of ESCC. Firstly, 48 differentially expressed miRNAs (DEMs) and 1319 differentially expressed genes (DEGs) were identified between 94 ESCC tissues and 13 normal esophageal tissues in TCGA.
View Article and Find Full Text PDFThe oxygen-deficient bismuth oxide, BiO, synthesized by a typical hydrothermal method using commercial NaBiO·2HO as a raw material only has a relatively low concentration of surface oxygen vacancies (OVs). How to improve the visible light photocatalytic performance of BiO via tuning its surface OV concentration is still a huge challenge. In this study, improving the surface OVs of BiO was successfully realized through the pretreatment of commercial NaBiO·2HO, including thermal treatment in air and hydrothermal treatment in 10 M NaOH solution, forming NaBiO·HO intermediate products first, and then hydrothermal preparation of BiO target products using NaBiO·HO instead of commercial NaBiO·2HO as the precursor.
View Article and Find Full Text PDFSynth Syst Biotechnol
September 2021
Biomarkers of disease, especially protein, show great potential for diagnosis and prognosis. For detecting a certain protein, a binding assay implementing antibodies is commonly performed. However, antibodies are not thermally stable and may cause false-positive when the sample composition is complicated.
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