Publications by authors named "Ruocheng Luo"
Article Synopsis
- - The study investigates the anti-inflammatory and anti-osteoclastogenesis properties of three types of Zanthoxylum seed oil (ZSO) derived from different species, specifically Zanthoxylum schinifolium, Zanthoxylum armatum, and Zanthoxylum bungeanum.
- - Using methods like Soxhlet extraction and GC-FID analysis, the researchers analyzed the fatty acid composition of these oils and tested their effects on inflammatory factors in LPS-induced macrophages through RT-qPCR and TRAP staining.
- - Results showed that all three ZSO types reduced inflammatory marker expression at a higher concentration, with ZSSO exhibiting the strongest anti-inflammatory effects; additionally, they effectively inhibited the formation
Article Synopsis
- * Four unsaturated fatty acids (oleic acid, linoleic acid, palmitoleic acid, and alpha-linolenic acid) were analyzed, with alpha-linolenic acid (ALA) showing the strongest effect in inhibiting osteoclast production and reducing inflammation in laboratory and animal studies.
- * The study suggests that ALA from ZBSO works through specific signaling pathways to lower harmful inflammatory markers, indicating that this oil could be a natural dietary option to prevent bone loss and related inflammation
Background: Geographic altitude is a potent environmental factor for human microbiota and bone mineral density. However, little evidence exists in population-based studies with altitude diversity ranges across more than 3000 m. This study assessed the associations between a wide range of altitudes and bone mineral density, as well as the potential mediating role of microbiota in this relationship.
View Article and Find Full Text PDFBackground: A growing body of studies have reported the health benefits of greenness. However, less is known about the potential beneficial effects of residential greenness on gut microbiota, which is essential to human health. In this study, we aim to examine the association between residential greenness and gut microbiota in a population-based cohort study.
View Article and Find Full Text PDFKnowledge about the impact of altitude and ethnicity on human oral microbiota is currently limited. To obtain the baseline of normal salivary microbiota, we analyzed the bacteria and fungi composition in Tibetan (HY group) and Han population (CD group) living at different altitudes by using next-generation sequencing (NGS) technology combined with PICRUSt and FUNGuild analyses. There were significant differences in oral microbiota composition between the two groups at phylum and genus levels.
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