Publications by authors named "Ruobing Li"

Employing a US national sample (N = 1041), this project investigates the relationship between media usage and vaccine hesitancy, as well as the potential variations in this relationship based on vaccine types and individuals' racial backgrounds. Findings revealed that participants held different levels of acceptance of different vaccines. Compared to other racial groups, African Americans held a lower level of positive attitudes toward different types of vaccines; however, racial groups did not differ significantly in terms of intention to receive vaccines.

View Article and Find Full Text PDF
Article Synopsis
  • - Ischemic stroke (IS) is a major type of stroke and a significant cause of death worldwide, with the mitochondrial-associated endoplasmic reticulum membrane (MAM) playing a key role in cellular communication.
  • - This literature review focuses on how MAM is involved in mitophagy (the process of recycling damaged mitochondria) and endoplasmic reticulum stress during IS.
  • - Important proteins like PINK1, FUNDC1, and Beclin1 are found in the MAM and help regulate mitochondrial health, while GRP78 and others manage stress responses, showing how these interactions may contribute to the development of IS.
View Article and Find Full Text PDF
Article Synopsis
  • * MA promotes autophagy in prostate cancer cells by increasing specific protein expressions and decreasing others, which helps with cell degradation and recycling.
  • * The study showed that MA also induces ferroptosis (a form of cell death) by manipulating certain metabolic pathways, and in vivo tests demonstrated that it significantly reduced tumor growth in mice.
View Article and Find Full Text PDF

For patients with resectable locally advanced esophageal squamous cell carcinoma (ESCC), the current standard treatment is neoadjuvant chemoradiotherapy (nCRT) plus radical surgery. This study aimed to establish a predictive model, based on computed tomography (CT) radiomics features and clinical parameters, to predict sensitivity to nCRT in patients with ESCC pre-treatment. The goal was to provide risk stratification and decision-making recommendations for clinical treatments and offer more valuable information for developing personalized therapies.

View Article and Find Full Text PDF

The communication of extreme weather forecasts (e.g., heatwaves and extreme precipitation) is a challenge for weather forecasters and emergency managers who are tasked with keeping residents safe during often unprecedented situations.

View Article and Find Full Text PDF

Objective: We aim to develop a predictive model for lymphovascular invasion (LVI) in patients with invasive breast cancer (IBC), using magnetic resonance imaging (MRI)-based radiomics features.

Methods: A total of 204 patients with IBC admitted to our hospital were included in this retrospective study. The data was split into training and validation sets at a 7:3 ratio.

View Article and Find Full Text PDF
Article Synopsis
  • Microproteins generated through unique translation processes are found in mitochondria, but their role in energy-demanding organs like the heart is not well understood.
  • This study identifies CD63-AS1 as a long non-coding RNA that encodes a mitochondrial microprotein named CEAM, which shows a connection to genes related to cardiomyopathy in human hearts.
  • CEAM can form resilient aggregates in mitochondria, and while its overexpression leads to mitochondrial stress and impaired cardiac function, it may provide protection during conditions like cardiac hypertrophy by suppressing harmful stress responses.
View Article and Find Full Text PDF

Cancer stem cells (CSCs) are most likely the main cause of lung cancer formation, metastasis, drug resistance, and genetic heterogeneity. Three-dimensional (3D) ex vivo cell culture models can facilitate stemness improvement and CSC enrichment. Considering the critical role of extracellular matrix (ECM) on CSC properties, the present study developed a thermo-responsive hydrogel using the porcine decellularized lung for 3D cell culture, and the cell-laden hydrogel culturing model was used to explore the CSC characteristics and potential utilization in CSC-specific drug evaluation.

View Article and Find Full Text PDF

Powdery mildew and stripe rust are major diseases on wheat worldwide that cause significant reductions in wheat production. The ribosomal silencing factor (RsfS) has been proven to regulate protein biosynthesis by inhibiting the translation process in bacterial response to stress. However, the role of RsfS in plant resistance to biotic stresses remains unclear.

View Article and Find Full Text PDF

To improve paste stability of cassava starch, including acid resistance, high-temperature shear resistance and freeze-thaw stability, cassava starch was modified by sequential maltogenic amylase and transglucosidase to form an optimally denser structure, or branched density (12.76 %), molecular density (15.17 g/mol/nm), and the proportions of short-branched chains (41.

View Article and Find Full Text PDF
Article Synopsis
  • Cardiomyocytes (CMs) experience significant structural and functional changes as they mature after birth, but the exact regulatory mechanisms are not fully understood; Cypher/ZASP is important for maintaining Z-disc stability and its deletion or mutation is linked to dilated cardiomyopathy (DCM).* -
  • Research using various techniques revealed that Cypher plays a critical role in CM maturation, with RNA sequencing identifying serum response factor (SRF) as a key regulatory transcription factor affected by the absence of Cypher.* -
  • The lack of Cypher disrupts proper sarcomere function and mitochondrial structure, leading to impaired cardiac function, but restoring SRF during the postnatal period can reverse these defects and improve overall cardiac performance
View Article and Find Full Text PDF

Purpose: This study aims to develop radiomics models and a nomogram based on machine learning techniques, preoperative dual-energy computed tomography (DECT) images, clinical and pathological characteristics, to explore the tumor microenvironment (TME) of clear cell renal cell carcinoma (ccRCC).

Methods: We retrospectively recruited of 87 patients diagnosed with ccRCC through pathological confirmation from Center I (training set, n = 69; validation set, n = 18), and collected their DECT images and clinical information. Feature selection was conducted using variance threshold, SelectKBest, and the least absolute shrinkage and selection operator (LASSO).

View Article and Find Full Text PDF

Aims: Circular RNAs (circRNAs) are considered important regulators of biological processes, but their impact on atherosclerosis development, a key factor in coronary artery disease (CAD), has not been fully elucidated. We aimed to investigate their potential use in patients with CAD and the pathogenesis of atherosclerosis.

Methods And Results: Patients with stable angina (SA) or acute coronary syndrome (ACS) and controls were selected for transcriptomic screening and quantification of circRNAs in blood cells.

View Article and Find Full Text PDF

This study investigates the role of dynamic fear in the effectiveness of communicating health threats (i.e. fear appeals) of ground-level ozone among Chinese citizens.

View Article and Find Full Text PDF

Introduction: Social media are important venues for youth's exposure to e-cigarette content. This study examined how exposure to user-generated e-cigarette content (i.e.

View Article and Find Full Text PDF
Article Synopsis
  • - Tumour incidence is rising annually, often linked to chromosomal instability and disrupted cell cycles, leading to DNA damage and gene mutations.
  • - NCAPG, a subunit of the non-SMC condensin I complex, plays a significant role in tumour development, with its high expression correlating with tumour growth and progression.
  • - This review aims to uncover the mechanisms by which NCAPG contributes to tumours, potentially offering new targets and strategies for cancer therapy and improving overall health outcomes.
View Article and Find Full Text PDF
Article Synopsis
  • Extracellular proteases, particularly chitinases from the fungus Arthrobotrys oligospora, aid in nematode infection, yet how microRNAs regulate gene expression in this context is not well understood.
  • Transcriptome sequencing was performed to identify and analyze chitin-responsive microRNAs (miRNAs), revealing that 25 out of 85 novel miRNAs significantly changed expression in response to chitin.
  • Target gene analysis indicated that these differentially expressed miRNAs (DEmiRNAs) are linked to biological processes like biodegradation and cell cycle regulation, while specific interactions, such as the chitinase AOL_s00004g379 being a target of miR_70, were confirmed through dual-luciferase assays.
View Article and Find Full Text PDF

Human behavior is largely influenced by social norms. While the social norm approach is frequently used in public health campaigns, their effectiveness is inconsistent. This study investigated the role of normative reactance - the amplification of subjective norms as a means of restoring threatened freedom - across two health behaviors: college drinking and STD testing.

View Article and Find Full Text PDF
Article Synopsis
  • - This study investigates how perceived threat and efficacy impact risk communication theories during public health crises, specifically looking at behavior changes.
  • - Using a two-part survey, the research shows that there's a complex relationship between people's belief in their ability to effectively respond (efficacy) and their perception of risk, which influences their protective behaviors.
  • - Interestingly, individuals who perceive high risk but feel less capable are more likely to take protective actions, challenging previous ideas about how people typically react to threats.
View Article and Find Full Text PDF

Objective: We investigated the potential of dual-energy computed tomography (DECT) radiomics in assessing cancer-associated fibroblasts in clear cell renal carcinoma (ccRCC).

Methods: A retrospective analysis was conducted on 132 patients with ccRCC. The arterial and venous phase iodine-based material decomposition images (IMDIs), virtual non-contrast images, 70 keV, 100 keV, and 150 keV virtual monoenergetic images, and mixed energy images (MEIs) were obtained from the DECT datasets.

View Article and Find Full Text PDF

Background: The incidence of perinatal depression is increasing and has become a global public health problem to be addressed.

Objective: To explore the prevention and treatment effects of different exercise methods on perinatal depression.

Methods: A meta-analysis was conducted by searching databases for published "exercise interventions for perinatal depression "related randomized controlled trials, up to July 20, 2022.

View Article and Find Full Text PDF

Wheat powdery mildew, caused by f. sp. (), is one of the most prevalent diseases of wheat worldwide and can lead to severe yield reductions.

View Article and Find Full Text PDF

A PHP Error was encountered

Severity: Warning

Message: fopen(/var/lib/php/sessions/ci_session37r12pv74ob9gup27f916iq8242dtt7t): Failed to open stream: No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 177

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: session_start(): Failed to read session data: user (path: /var/lib/php/sessions)

Filename: Session/Session.php

Line Number: 137

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once