Publications by authors named "Ruobai Lin"

Objective: To compare the perioperative complications between Ivor-Lewis approach and McKeown approach in minimally invasive esophagectomy and gastric tube reconstruction for the treatment of middle and lower thoracic esophageal cancer.

Methods: Retrospective analysis of clinical data was performed on 288 patients with middle and lower thoracic esophageal cancer who underwent completely minimally invasive esophagectomy by one surgical team in Fujian Medical University Union Hospital from December 2010 to March 2014. Among the 288 patients, 103 patients underwent combined laparoscopic and thoracoscopic esophagectomy and intrathoracic esophagogastric anastomosis using a transoral anvil(Orvil)(Ivor-Lewis group, 2-incision) and 185 patients underwent combined laparoscopic and thoracoscopic esophagectomy and cervical anastomosis(McKeown group, 3-incision).

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Background: Complete video-assisted thoracoscopic surgery (c-VATS) for left upper lobectomy is difficult due to the branching pattern of the left pulmonary artery.

Objective: Our purpose was to report outcomes of a modified technique of c-VATS left upper lobectomy.

Methods: We retrospectively compared the outcomes of 83 patients with stage I/II non-small-cell lung cancer (NSCLC) who received left upper lobectomy between 2008 and 2011; 32 underwent conventional c-VATS and 50 received modified c-VATS.

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Objectives: The aim of this study is to compare thoracoscopic mobilization of the oesophagus in the lateral decubitus position and the semiprone position and to identify potential differences between the two techniques.

Methods: A retrospective review of a prospectively maintained oesophagectomy database identified 150 patients undergoing combined thoracoscopic and laparoscopic oesophagectomy (TLO). Of these, 90 cases underwent thoracoscopic oesophageal mobilization in the left lateral decubitus position.

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Objective: To summarize early experience in combined thoraco-laparoscopic esophagectomy with two-field lymph node dissection for esophageal carcinoma.

Methods: A total of 150 patients with thoracic esophageal cancer who underwent combined thoracoscopic and laparoscopic esophagectomy in Union Hospital, Fujan Medical University, were enrolled in this study.

Results: Locations of the tumors included upper esophagus (n=14), middle esophagus (n=95), and lower esophagus (n=41).

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Objectives: The aim of this study was to assess the experience of a high-volume centre with thoracolaparoscopy radical oesophagectomy and to evaluate the feasibility, tumour clearance, the learning curve and reproducibility of this technique.

Methods: Eighty patients with thoracic oesophageal cancer who underwent thoracolaparoscopic oesophagectomy (TLE) were enrolled in this study. Two attending surgeons (Mingqiang Kang and Ruobai Lin) independently performed the procedure as operating surgeons.

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Article Synopsis
  • A genome-wide association study was conducted on esophageal squamous cell carcinoma (ESCC) involving 1,077 ESCC patients and 1,733 control subjects, focusing on the Chinese Han population.
  • The study successfully replicated findings in larger cohorts, identifying two new genetic risk factors for ESCC: PLCE1 and C20orf54, with strong statistical significance.
  • PLCE1 is linked to essential cellular functions like growth and apoptosis, while C20orf54 is involved in riboflavin transport, highlighting their potential roles in ESCC and gastric cardia adenocarcinoma (GCA) risk.
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Background: Preoperative lung cancer with mediastinal lymph nodes metastasis can be diagnosed by vedio mediastinoscopy (VM) and CT. This study was to explore the value of VM and CT in the diagnosis of N staging of preoperative lung cancer, and to discuss the difference between the two methods.

Methods: Forty-eight cases diagnosed of lung cancer by CT or PET-CT were examined by VM.

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Objective: To discuss the application value of video-assisted thoracoscopic surgery (VATS) in treatment of esophageal leiomyoma.

Method: Clinical data of patients with esophageal leiomyoma treated by VATS from January 1999 to August 2007 were analyzed.

Results: VATS esophageal leiomyoma enucleations were performed successfully in 23 patients, and 18 patients of them were performed by pure VATS, 5 patients of them were performed with mini-thoracotomy.

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Article Synopsis
  • Scientists wanted to see if using a special virus to deliver a gene called hIL-10 into transplanted lungs could help protect them from damage.
  • They did tests on 56 male rats, dividing them into four groups with different treatments, including one group that received the hIL-10 gene.
  • Results showed that the group with hIL-10 had better lung function and less damage compared to the other groups.
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Background & Objective: It is still very difficult to make a definite diagnosis for some mediastinal diseases through some examinations, such as CT scan and fibrobronchoscopy. To judge the metastasis of mediastinal lymph nodes exactly for lung cancer patients and make proper staging of lung cancer are important for defining therapeutic schedule and estimating prognosis. This study was to explore the application value and summarize the experience of mediastinoscopy in the diagnosis of mediastinal diseases and the staging of lung cancer with enlarged mediastinal lymph nodes.

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Objective: To study the mechanism of delayed emptying indigestible solids in thoracic stomach after the resection of esophageal cancer by monitoring the variety of antropyloroduodenal migrating motor complex (MMC) during interdigestion.

Methods: Esophagectomy and gastroesophagostomy in the neck was performed in 5 men with esophageal cancer. An eight-lumen manometric sleeve assembly was passed through a nostril into the duodenum during operation.

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