Cyber warfare: a study of Zelenskyy's social media political performance strategies and effects.

During the Russia-Ukraine war, Ukrainian President Volodymyr Zelenskyy has strategically used social media to appeal for international support. This reflects a broader trend of political figures relying on digital platforms to shape public opinion and influence global narratives during crises. This work uses three main analysis methods, content, sentiment and social network analysis.

Aerosol light absorption alleviates particulate pollution during wintertime haze events.

Aerosol light absorption has been widely considered as a contributing factor to the worsening of particulate pollution in large urban areas, primarily through its role in stabilizing the planetary boundary layer (PBL). Here, we report that absorption-dominated aerosol-radiation interaction can decrease near-surface fine particulate matter concentrations ([PM]) at a large-scale during wintertime haze events. A "warm bubble" effect by the significant heating rate of absorbing aerosols above the PBL top generates a secondary circulation, enhancing the upward motion (downward motion) and the convergence (divergence) in polluted (relatively clean) areas, with a net effect of lowering near-surface [PM].

Spatiotemporal Nano-Regulator Unleashes Anti-Tumor Immunity by Overcoming Dendritic Cell Tolerance and T Cell Exhaustion in Tumor-Draining Lymph Nodes.

Lymph nodes are crucial immune foci as the primary target for cancer immunotherapy. However, the anti-tumor functions of tumor-draining lymph nodes (TDLNs) are critically suppressed by tumors. Here, a novel spatiotemporal nano-regulator is presented, designed to modulate the dendritic cells (DCs) in TDLNs, establishing a supportive niche for immune surveillance.

Epigenetic regulation of organ-specific functions in Mikania micrantha and Mikania cordata: insights from DNA methylation and siRNA integration.

Background: DNA methylation is a crucial epigenetic mechanism that regulates gene expression during plant growth and development. However, the role of DNA methylation in regulating the organ-specific functions of the invasive weed Mikania micrantha remains unknown.

Results: Here, we generated DNA methylation profiles for M.

Ethylene modulates wheat response to phosphate deficiency.

Ethylene involves in the response to P deficiency in some model plants, but its relevance to wheat remains limited. Following our recent study demonstrating the role of differentially expressed genes (DEGs) encoding ethylene response factors (ERFs) in response to P starvation in wheat, this study aims to investigate the remodelling of ethylene pathway and the physiological roles of ethylene in wheat under P deficiency using transcriptome analysis and the addition of exogenous ethylene analogue ethephon or ethylene inhibitors. ERFs with at least a two-fold change upon P deficiency were biasedly enriched on chromosome 4 B.

USP30-AS1 Suppresses Colon Cancer Cell Inflammatory Response Through NF-κB/MYBBP1A Signaling.

Colorectal cancer (CRC) is one of the most prevalent malignancies worldwide and poses a significant threat to human health. Recent studies have underscored the crucial role of aberrant expression of long non-coding RNAs (lncRNAs) in the initiation and progression of CRC. In this study we identified that lncRNA USP30-AS1 is significantly downregulated in colorectal cancer tissues, particularly in the advanced stages of the disease.

MoS/porous carbon nanofiber heterostructures for efficient evaporation-driven generators.

Evaporation power generators (EPGs) based on natural water evaporation can directly convert heat energy from the surrounding environment into electrical energy. Nevertheless, the commercialization of EPGs faces challenges due to the low charge generation and transport efficiency of single material systems, leading to unsatisfactory open-circuit voltages and short-circuit currents. Here, we systematically prepared molybdenum sulfide (MoS)/porous carbon nanofiber (PCNF) heterogeneous systems by electrospinning and hydrothermal methods.

Functional identification of carbohydrate-binding module 13 and its application to quantification of hemicellulose in gramineous plants.

Gramineous biomass is a type of lignocellulose commonly used as a renewable energy source. Accurate quantification of hemicellulose within this biomass is crucial for its efficient conversion. Carbohydrate-binding modules (CBMs) help catalytic domains anchor substrates, representing the potential to be developed as fluorescence probes for hemicellulose content determination.

A lightweight model design approach for few-shot malicious traffic classification.

Classifying malicious traffic, which can trace the lineage of attackers' malicious families, is fundamental to safeguarding cybersecurity. However, the deep learning approaches currently employed require substantial volumes of data, conflicting with the challenges in acquiring and accurately labeling malicious traffic data. Additionally, edge network devices vulnerable to cyber-attacks often cannot meet the computational demands required to deploy deep learning models.

Association between dietary -carotene intake with Parkinson's disease and all-cause mortality among American adults aged 40 and older (NHANES 2001-2018).

Background: The existing evidence concerning the correlation between dietary -carotene intake and Parkinson's disease (PD) is currently deemed insufficient. Thus, this research aims to investigate the relationship between dietary -carotene intake and both the prevalence of PD and all-cause mortality within the US (United States) population.

Methods: The research employed cross-sectional analysis and cohort studies utilizing data from 16,852 participants in the National Health and Nutrition Examination Survey (NHANES) spanning from 2001 to 2018.

Cytokine-armed vaccinia virus promotes cytotoxicity toward pancreatic carcinoma cells via activation of human intermediary CD56CD16 natural killer cells.

Pancreatic ductal adenocarcinoma (PDAC) remains a particularly aggressive disease with few effective treatments. The PDAC tumor immune microenvironment (TIME) is known to be immune suppressive. Oncolytic viruses can increase tumor immunogenicity via immunogenic cell death (ICD).

Clinical prognosticators and targets in the immune microenvironment of intrahepatic cholangiocarcinoma.

Background: Intrahepatic cholangiocarcinoma (ICC) is a disease with poor prognosis and limited therapeutic options. We investigated the tumor immune microenvironment (TIME) to identify predictors of disease outcome and to explore targets for therapeutic modulation.

Methods: Liver tissue samples were collected during 2008-2019 from patients ( = 139) diagnosed with ICC who underwent curative intent surgery without neoadjuvant chemotherapy.

Protective Effect of Modified Ginseng Baidu Powder Prophylactic Administration on LPS-Induced Acute Respiratory Distress Syndrome in Mice.

Severe Corona Virus Disease 2019 (COVID-19) patients may develop acute respiratory distress syndrome (ARDS). Modified Ginseng Baidu Powder (referred to as Baidu Powder) was used for respiratory system diseases caused by colds. To study the effect of Baidu Powder on protecting ARDS mice model and its underlying active ingredients and targets intervening in COVID-19.

Insulin-like growth factor-binding protein 7 exacerbates inflammatory response and lipid metabolism imbalance in alcohol-associated liver disease.

Alcohol-associated liver disease(ALD), caused by excessive alcohol consumption, are often associated with inflammatory outbreaks and lipid deposition in the liver. The role of Insulin-like growth factor-binding protein 7 (IGFBP7), an important metabolic regulator, in ALD, its underlying regulatory mechanism, and its potential implication in anti-ALD therapies remain unknown. We investigated the effects of IGFBP7 on hepatic inflammation and lipid metabolism disruption in a mouse model of ALD.

Burden of non-communicable diseases attributable to high temperature in a changing climate from 1990 to 2019: a global analysis.

Background: With global climate change, the health threats of ambient high temperature have received widespread attention. However, latest spatio-temporal patterns of the non-communicable diseases (NCDs) burden attributable to high temperature have not been systematically reported. We aimed to analyze vulnerable areas and populations based on a detailed profile for the NCDs burden attributable to high temperature globally.

Prognostic value of transient ischemic dilatation by N-ammonia PET MPI for short-term outcomes in patients with non-obstructive CAD.

Objective: Transient ischaemic dilatation (TID) had incremental diagnostic and prognostic value in obstructive coronary artery disease (CAD), but its clinical significance in patients with non-obstructive CAD remains unknown. We aimed to explore the prognostic value of TID in patients with non-obstructive CAD by N-ammonia PET imaging.

Methods: We retrospectively studied 131 consecutive patients with non-obstructive CAD undergoing one-day rest-stress N-ammonia PET myocardial perfusion imaging (MPI).

Controlling charge migration and CO conversion through surface decoration of 2D-hydrotalcite on bismuth oxybromide for enhanced artificial photosynthesis.

Photocatalytic reduction of CO in pure HO media to produce chemicals presents an appealing avenue for simultaneously alleviating energy and environmental crises. However, the rapid recombination of photogenerated charge carriers presents a significant challenge in this promising field. Heterojunction engineering has emerged as an effective approach to address this dilemma.

β-Hydroxybutyrate alleviates brain aging through the MTA1 pathway in D-galactose injured mice.

Aging is an inevitable law of the process of life during which many physiological functions change. Brain aging is an important mechanism in the occurrence and development of degenerative diseases of the central nervous system. β-Hydroxybutyrate (BHBA) is a water-soluble, endogenous small-molecule ketone that can cross the blood-brain barrier and induce neuroprotective effects.

A Novel Time-Frequency Parameterization Method for Oscillations in Specific Frequency Bands and Its Application on OPM-MEG.

Time-frequency parameterization for oscillations in specific frequency bands reflects the dynamic changes in the brain. It is related to cognitive behavior and diseases and has received significant attention in neuroscience. However, many studies do not consider the impact of the aperiodic noise and neural activity, including their time-varying fluctuations.

Coupling effects of irrigation and nitrogen on spring maize yield and greenhouse gas emissions in Northwestern China.

Background: This study explored the mechanism of irrigation and nitrogen (N) coupling on spring maize yield and soil greenhouse gas (GHG) emissions, with the objective of achieving water saving, high yield and emission reduction. Field experiments were conducted to analyze the effects of multiple irrigation and N management strategies on GHG emissions and to determine the optimal balance between GHG, water conservation and grain yield. The experiments were conducted on spring maize with three irrigation levels (low, IL; medium, IM; and high, IH) and 4 N application levels (N40, N80, N120 and N160 kg N ha).

Prognostic Value of Resting Left Ventricular Sphericity Indexes in Coronary Artery Disease With Preserved Ejection Fraction.

Background: Adverse left ventricular remodeling is a significant cardiovascular predictor for patients with coronary artery disease and preserved left ventricular ejection fraction (LVEF). However, the remodeling indexes reflecting left ventricular spherization by myocardial perfusion imaging are underexplored.

Methods And Results: 727 patients (mean age 59.