Publications by authors named "Ruo-Liu Wang"
[Analysis of chemical constituents in Shenmai Injection by LC-Q-TOF-MS and LC-IT-MS].
Zhongguo Zhong Yao Za Zhi
February 2020
The chemical constituents in Shenmai Injection(SMI) were qualitatively analyzed by using liquid chromatography/quadrupole time-of-flight mass spectrometry(LC-Q-TOF-MS) and liquid chromatography-ion trap-mass spectrometry(LC-IT-MS). The analysis was performed on an Agilent Zorbax SB-C_(18)(4.6 mm×250 mm, 5 μm) and gradient elution was carried out with 0.
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- The study focuses on Zhi-Shi-Zhi-Zi-Chi-Tang (ZSZZCT), a traditional Chinese medicine, and its anti-inflammatory properties through advanced analytical methods like LC-MS and NMR.
- Researchers detected 79 chemical constituents from the whole extract, identifying 39 of them either definitively or tentatively.
- Four polymethoxyl flavones were highlighted as key active ingredients, and three specific ones demonstrated significant anti-inflammatory effects, confirming the effectiveness of the activity index approach in identifying active components in traditional Chinese medicine.