Publications by authors named "Ruo-Jin Ren"
[Studies on multidrug resistance associated protein in retinoblastoma].
Zhonghua Yan Ke Za Zhi
April 2009
Article Synopsis
- This study aimed to detect the expression of multidrug resistance markers (P-glycoprotein, lung resistance associated protein, and multidrug resistance associated protein) in retinoblastoma and explore their relationship with clinic-pathological factors.
- Seventy-five retinoblastoma cases were analyzed using immunohistochemical methods, finding rates of positive expression for the markers and correlations between them.
- The results indicated that all three proteins significantly correlate with tumor differentiation, suggesting that their combined effects contribute to the intrinsic multidrug resistance seen in retinoblastoma.
Eyelid neoplasms in the Beijing Tongren Eye Centre between 1997 and 2006.
Ophthalmic Surg Lasers Imaging
October 2008
Background And Objective: To examine the spectrum of eyelid neoplastic specimens obtained at the Beijing Tongren Eye Centre between 1997 and 2006.
Patients And Methods: A total of 2,639 eyelid neoplasms were included in the study.
Results: Of the 2,639 eyelid specimens, 2,276 (86.
[Clinical and pathological analysis of 2639 cases of eyelid tumors].
Zhonghua Yan Ke Za Zhi
January 2008
Objective: To describe the histopathologic spectrum and patient characteristics of eyelid tumors in Beijing Tongren Hospital.
Methods: It was a claims database analysis. A total of 2639 eyelid tumors verified histopathologically from January 1997 to December 2006 were included in the study.
[Study on the risk factors for optic nerve invasion in 381 cases of retinoblastoma].
Zhonghua Yan Ke Za Zhi
June 2007
Objective: To investigate the clinical and pathologic outcomes of a large group of retinoblastoma (RB) cases to ascertain the risk factors of RB optic nerve invasion.
Methods: In this paper, we summarized the clinical and pathologic data of 381 retinoblastoma cases in Beijing Tongren Hospital observed from 1990 to 2002. Statistical analyses were performed on the sex, age, unilateral or bilateral cases, length of symptoms, clinical situation, stage, histological type and the degree of optic nerve invasion.
[The effects of matrine on cell proliferation and telomerase activity in retinoblastoma cells in vitro].
Zhonghua Yan Ke Za Zhi
July 2006
Objective: To evaluate the effects of matrine on cell proliferation and telomerase activity in retinoblastoma cells in vitro.
Methods: HXO-Rb44 cells were treated with 0.1 to 3.
[The study on the correlation between telomerase and histopathologic features of retinoblastoma].
Zhonghua Yan Ke Za Zhi
April 2004
Objective: To investigate the correlation between the expression of human telomerase RNA (hTR), human telomerase reverse transcriptase (hTRT) and the proliferation and differentiation of retinoblastoma (RB).
Methods: In 37 RB specimens, the expression of hTR and hTRT was investigated with the methods of in situ hybridization (ISH). Immunohistochemical method was performed to detect the expression of proliferating cell nuclear antigen (PCNA) in RB.