Publications by authors named "Ruo-Chen Yan"
Article Synopsis
- - MELK (Maternal embryonic leucine zipper kinase) is part of the AMPK family and is found in high levels in various cancers, playing a critical role in tumor cell survival, growth, and movement.
- - It also influences the tumor microenvironment, which can help predict how tumors will respond to immunotherapy and affects immune cell functions that regulate tumor growth.
- - The development of small molecule inhibitors targeting MELK has shown promising anti-tumor effects in clinical trials, making MELK a potential therapeutic target for cancer treatment, though many of its mechanisms are still not fully understood.
