In this editorial we comment on the article by Ji . We focus specifically on the EGFR tyrosine kinase inhibitor (EGFR-TKI) treatment and the development of drug resistance to EGFR-TKIs.
The review focuses on how SARS-CoV-2 (the virus causing COVID-19) affects the liver, highlighting the presence of specific receptors in liver cells that facilitate viral entry and potentially lead to liver damage.
Many COVID-19 patients exhibit liver dysfunction, characterized by elevated enzyme levels, and those with pre-existing chronic liver diseases face higher risks of severe outcomes.
The study also emphasizes the need for further research into the safety and effectiveness of COVID-19 vaccines and treatments in patients with chronic liver conditions.