Publications by authors named "Runtian Chen"

Article Synopsis
  • Sjögren syndrome (SS) is a common autoimmune disorder primarily affecting exocrine glands, leading to symptoms like dry eyes and mouth, but often goes undiagnosed.
  • A 22-year-old female exhibited uncommon symptoms such as hypokalemic paralysis and severe bone pain, prompting an extensive diagnostic evaluation.
  • After confirming distal renal tubular acidosis as a complication of SS, the patient received targeted treatment, resulting in significant improvement within two weeks, highlighting the need for awareness and prompt treatment of SS in younger patients.
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Objective: Hypertension predicts the development of diabetes. However, there are still lacking high-quality studies on the correlation between mean arterial pressure (MAP) and incident diabetes. We aimed to explore the relationship between MAP and diabetes in Chinese adults.

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We aimed to establish and validate a risk assessment system that combines demographic and clinical variables to predict the 3-year risk of incident diabetes in Chinese adults. A 3-year cohort study was performed on 15,928 Chinese adults without diabetes at baseline. All participants were randomly divided into a training set ( = 7,940) and a validation set ( = 7,988).

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Background: Reliable quantification of the relationship between hypertension and diabetes risk is limited, especially among Chinese people. We aimed to investigate the association between hypertension and the risk of diabetes in a large cohort of the Chinese population.

Methods: This was a retrospective propensity score-matched cohort study among 211,809 Chinese adults without diabetes at baseline between 2010 and 2016.

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Objective: To use latent class analysis to identify unobservable subpopulations amongst the heterogeneous population and explore the relationship between subpopulations and incident diabetes among Chinese adults.

Methods: The retrospective study included 32,312 Chinese adults without diabetes at baseline. Latent class indicators included demographic and clinical variables.

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Identifying individuals at high risk for incident diabetes could help achieve targeted delivery of interventional programs. We aimed to develop a personalized diabetes prediction nomogram for the 3-year risk of diabetes among Chinese adults. This retrospective cohort study was among 32,312 participants without diabetes at baseline.

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Background: Glycosylated hemoglobin (HbA1c) has a detrimental impact on the myocardium with left ventricular (LV) diastolic dysfunction. Obesity is a risk factor of type 2 diabetes. To understand the relationships between HbA1c, body mass index (BMI) and LV diastolic dysfunction, we performed this interaction analysis in patients with type 2 diabetes.

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