Publications by authors named "Runmin Ding"
Infection with Toxoplasma gondii (T. gondii) during the pregnant period causes microcephaly, mental and psychomotor retardation or death. Miserable outcomes are mainly linked with regulatory T cells (Tregs) dysfunction.
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- Infection during pregnancy can lead to severe outcomes for the fetus and offspring, including conditions like microcephaly and death.
- The infection is commonly transmitted through undercooked meat or contaminated food and water.
- The review focuses on how this infection disrupts regulatory T cells (Tregs) and their crucial transcriptional factor, Foxp3, which are vital for maternal-fetal immune tolerance and fetal development.