Fully automated structured light scanning for high-fidelity 3D reconstruction via graph optimization.

Convenient and high-fidelity 3D model reconstruction is crucial for industries like manufacturing, medicine and archaeology. Current scanning approaches struggle with high manual costs and the accumulation of errors in large-scale modeling. This paper is dedicated to achieving industrial-grade seamless and high-fidelity 3D reconstruction with minimal manual intervention.

Nanoengineered Supramolecular Adhesive Sponge for Rapid Hemostasis and Abdominal Wall Wound Healing.

Multifunctional dressing biomaterials that can promote tissue adhesion, hemostasis, and soft-tissue wound healing are of great clinical significance. Here, we report a nanocomposite supramolecular sponge constructed by an air-in-water emulsion template composed of methacrylated gelatin (GelMA), Laponite nanoclay, and branched supramolecular polymer (PAMU). The sponge has an interconnected macroporous structure and exhibits tunable mechanical properties with varying Laponite concentration.

Information Difference of Transfer Entropies between Head Motion and Eye Movement Indicates a Proxy of Driving.

Visual scanning is achieved via head motion and gaze movement for visual information acquisition and cognitive processing, which plays a critical role in undertaking common sensorimotor tasks such as driving. The coordination of the head and eyes is an important human behavior to make a key contribution to goal-directed visual scanning and sensorimotor driving. In this paper, we basically investigate the two most common patterns in eye-head coordination: "head motion earlier than eye movement" and "eye movement earlier than head motion".

Electrodeposition of Self-Supported High-Entropy Spinel Oxides for Stable Oxygen Evolution.

Spinel oxides have attracted increasing interest due to their excellent activity in the oxygen evolution reaction (OER). However, despite the high intrinsic OER activity, their poor electrical conductivity and weak structural stability prevented their application for a long time. These shortcomings can be solved by effectively adjusting the electronic structures of spinel oxides through a high-entropy strategy.

A "peptide-target-aptamer" electrochemical biosensor for norovirus detection using a black phosphorous nanosheet@TiC-Mxene nanohybrid and magnetic covalent organic framework.

Norovirus (NoV) is a major foodborne pathogen responsible for acute gastroenteritis epidemics, and establishing a robust detection method for the timely identification and monitoring of NoV contamination is of great significance. In this study, a peptide-target-aptamer sandwich electrochemical biosensor for NoV was fabricated using Au@BP@TiC-MXene and magnetic Au@ZnFeO@COF nanocomposites. The response currents of the electrochemical biosensor were proportional to the NoV concentrations ranging from 0.

Injectable Supramolecular Hybrid Hydrogel Delivers IL-1β-Stimulated Exosomes to Target Neuroinflammation.

Long-term neuroinflammation is a major barrier to neurological recovery after cerebral ischemia-reperfusion injury (CIRI). Here, a thermosensitive injectable supramolecular hybrid hydrogel is developed to sustainably deliver exosomes derived from interleukin-1β-stimulated bone marrow stromal cells (BMSCs) (βExos) with improved exosome production and anti-inflammatory capacity for neuroinflammation inhibition and neurological recovery. The supramolecular hydrogel displays self-healing and injectable features, along with high biocompatibility and tissue-like softness.

Electrochemical sensor for human norovirus based on covalent organic framework/pillararene heterosupramolecular nanocomposites.

Noroviruses are the leading cause of acute gastroenteritis and food-borne diseases worldwide. Thus, a rapid, accurate, and easy-to-implement detection method for controlling infection and monitoring progression is urgently needed. In this study, we constructed a novel sandwich-type electrochemical biosensor integrated with two specific recognition elements (aptamer and peptide) for human norovirus (HuNoV).

Injectable Supramolecular Hydrogel for Locoregional Immune Checkpoint Blockade and Enhanced Cancer Chemo-Immunotherapy.

Immunotherapy has revolutionized the therapeutic modalities of cancer treatment but is severely limited by a low objective response rate and the risk of immune-related side effects. Herein, an injectable supramolecular hydrogel is developed for local delivery of the PPA-1 peptide (a d-peptide antagonist with a high binding affinity to programmed cell death-ligand 1 (PD-L1)) and doxorubicin (DOX). On the one hand, DOX could kill tumor cells directly and also induce immunogenic cell death to provoke the antitumor immune response.

Dynamical heterogeneity in the gelation process of a polymer solution with a lower critical solution temperature.

The gelation of a hydrophobically modified hyaluronic acid aqueous solution which shows a lower critical solution temperature of about 25 °C was investigated by multi-particle tracking microrheology. The linear viscoelasticity of the gelling system is converted from the microrheological data. The critical gelling temperature T = 36.

Facile synthesis of hierarchical and porous V2O5 microspheres as cathode materials for lithium ion batteries.

Hierarchical and porous V2O5 microspheres have been fabricated by a refluxing approach followed by annealing in air. The resulting porous V2O5 microspheres typically have diameters of 3-6 μm and are constructed of intertwined laminar nanocrystals or crosslinked nanobricks. It is found that the vanadyl glycolates rinsed with water have pronounced pore structures than that rinsed with ethanol alone.

Orthostatic effects of midodrine versus L-NAME on cerebral blood flow and the renin-angiotensin-aldosterone system in tetraplegia.

Objective: To compare responses to head-up tilt (HUT) in individuals with chronic tetraplegia after midodrine hydrochloride (10 mg) versus nitro-L-arginine methyl ester (L-NAME, 1 mg/kg) administration.

Design: Prospective comparative drug trial.

Setting: Veterans Affairs medical center.

Acute suppression of bone turnover with calcium infusion in persons with spinal cord injury.

Background: Some people with chronic spinal cord injury (SCI) have low vitamin D levels and secondary hyperparathyroidism.

Objective: To determine whether, and to what extent, an acute calcium infusion decreased levels of N-telopeptide (NTx), a marker of osteoclastic activity, in individuals with chronic SCI.

Study Design: Case series.

Orthostatic responses to nitric oxide synthase inhibition in persons with tetraplegia.

Objectives: To determine the effects of 1.0 mg/kg nitro-L-arginine methyl ester (L-NAME) on orthostatic mean arterial pressure (MAP), serum aldosterone, and plasma renin concentrations in persons with chronic tetraplegia compared with nonspinal cord-injured controls.

Design: Prospective placebo-controlled intervention study.

Effect of a vitamin D analog on leg bone mineral density in patients with chronic spinal cord injury.

A randomized, placebo-controlled trial was performed to determine the effect of a vitamin D analog (1-alpha-hydroxyvitamin D(2) [1-alpha D(2)]) on the bone mineral density (BMD) in patients with chronic spinal cord injury (SCI). Forty subjects with chronic complete motor SCI were enrolled. The mean plus or minus standard deviation age and duration of injury were 42 plus or minus 12 yr and 11 plus or minus 10 yr, respectively.

Effect of low-dose baclofen administration on plasma insulin-like growth factor-I in persons with spinal cord injury.

Patients with chronic spinal cord injury (SCI), a condition associated with reduced physical function, have been reported to have lower plasma insulin-like growth factor-I (IGF-I) levels than able-bodied persons. We evaluated the potential for daily low-dose baclofen administered over several weeks to increase plasma IGF-I levels. Ten healthy male outpatients with chronic SCI were studied prospectively.