Publications by authors named "Runjuan Tang"
Article Synopsis
- Previous research established circRNAs as key players in the progression of cancer stem cells (CSCs), particularly their role in tumor development, prompting this study to explore circ_0000972's influence on hepatocellular carcinoma (HCC) CSCs.
- The study utilized techniques like RT-qPCR and xenograft models to analyze the expression of circ_0000972, miR-96-5p, and PFN1, finding that circ_0000972 overexpression led to reduced tumor cell characteristics and sizes by affecting EMT processes.
- The mechanisms revealed that circ_0000972 functions as a sponge for miR-96-5p, which in turn boosts PFN1 expression, highlighting its
Background: Circular RNAs (circRNAs) have been uncovered to play an important regulatory function in the tumorigenesis of intrahepatic cholangiocarcinoma (ICC). Hsa_circ_0,019,054 was found to be increased in ICC. Here, we aimed to explore the action and mechanism of hsa_circ_0,019,054 in ICC carcinogenesis.
View Article and Find Full Text PDFBackground: Recent studies indicate that circular RNA (circRNA) serves important roles in the development of intrahepatic cholangiocarcinoma (ICC). However, the role of circRNA reticulon 4 interacting protein 1 (circRTN4IP1) in ICC progression remains unknown.
Methods: Expression of circRTN4IP1, microRNA-541-5p (miR-541-5p), hypoxia inducible factor 1 subunit alpha (HIF1A) and other indicated protein markers was detected by quantitative real-time polymerase chain reaction or Western blot.