A self-catalyzed, visible-light-induced, directly selective C3-H aroylation of quinoxalin-2(1)-ones via energy transfer and hydrogen atom transfer (HAT) catalysis has been developed. The method is highly atom-economical, eco-friendly, and easy to handle. Notably, the reaction proceeded efficiently with ambient air as the sole oxidant at room temperature.
View Article and Find Full Text PDFMelanoma is highly resistant to most traditional treatments; therefore, its incidence and mortality rates are rapidly increasing. The effect of a novel sansalvamide A analogue named LY-15 on the growth and induction of apoptosis in B16 cancer cells was investigated . The inhibitory effects of LY-15 on B16 cells occurred in a concentration- and time-dependent manner.
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