Publications by authors named "Runjia Hua"

Article Synopsis
  • The study investigates the effectiveness of two surgical treatments for Stage III Kümmell's disease without neurological deficits: percutaneous kyphoplasty (PKP) and pedicle subtraction osteotomy (PSO) combined with long-segment fixation (LSF).
  • A total of 89 patients were treated, with results showing that the PKP group had quicker recovery metrics and lower disability scores post-surgery, while the PSO+LSF group achieved better spinal alignment corrections.
  • Ultimately, both procedures were effective with similar complication rates, suggesting personalized treatment plans based on patient's condition and surgeon’s expertise are crucial.
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NUAK2 is a member of the AMP-activated protein kinase (AMPK) family, which plays an essential role in cellular processes such as apoptosis, proliferation, and cell fate. Recent studies have already shown that silencing of NUAK2 blocks proliferation and promotes apoptosis of human melanoma cells and liver cancer cells. In addition, NUAK2 is involved in the development of glioblastoma via regulating the expression of cancer stem cell-related genes, and it promotes the cell cycle entry in the glioblastoma cells.

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Objective: The aim of this study was to verify the biomechanical properties of a newly designed angulated lateral plate (mini-LP) suited for two-level oblique lumbar interbody fusion (OLIF). The mini-LP is placed through the lateral ante-psoas surgical corridor, which reduces the operative time and complications associated with prolonged anesthesia and placement in the prone position.

Methods: A three-dimensional nonlinear finite element (FE) model of an intact L1-L5 lumbar spine was constructed and validated.

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