Publications by authors named "Rungrapat Muanaum"
Safety and efficacy of CKBM-A01, a Chinese herbal medicine, among asymptomatic HIV patients.
Southeast Asian J Trop Med Public Health
May 2009
Complementary remedies represent a potential alternative treatment for chronic diseases, including HIV/AIDS cases not meeting criteria for using highly active antiretroviral therapy (HAART). This study evaluated the safety and efficacy of CKBM-A01, a Chinese herbal medicine, and patient quality of life (QoL). Asymptomatic HIV patients with CD4 counts of 250-350 cells/microl were recruited into this open-labeled trial.
View Article and Find Full Text PDF6-month evaluation of JinHuang Chinese herbal medicine study in asymptomatic HIV infected Thais.
Wirach Maek-a-nantawat Punnee Pitisuttithum Valai Bussaratid Supat Chamnachanan Supa Naksrisook Rungrapat Muanaum
Southeast Asian J Trop Med Public Health
June 2003
Article Synopsis
- Good results from an in vitro study on JinHuang, a Chinese herbal medicine, prompted an in vivo study to assess safety and efficacy in asymptomatic HIV-infected individuals.
- An open study involving 21 Thai volunteers (12 females, 9 males) took place, with participants taking JinHuang for 6 months, monitored closely for side effects.
- Reported side effects included increased bowel movements (81%) and changes in taste/smell (52%), but no serious adverse events were noted; however, there were no significant changes in viral load or CD4 count, though many participants felt improvements in quality of life.
Article Synopsis
- The study focused on understanding the role and commitment of volunteers in HIV vaccine trials, highlighting concerns about risk behaviors and volunteers’ expectations throughout the trial process.
- Conducted with 164 volunteers, the study found no increase in risky behavior, and a significant decrease in risky sexual practices over time, demonstrating positive behavioral changes among participants.
- Volunteers reported favorable outcomes from their involvement, including knowledge gain and positive social contributions, reflecting their overall beneficial expectations from participating in the vaccine trials.