Proteomic Analysis Reveals Proteins Involved in the Mode of Action of β-Citronellol Identified From DC. Leaf Against .

is a fungus that lives primarily on the mucosal surfaces of healthy humans, such as the oral cavity, vagina, and gastrointestinal tract. This commensal organism can be controlled by other microbiota, while certain conditions can increase the risk of outgrowth and cause disease. Prevalence of the drug-resistant phenotype, as well as the severity of infection in immunocompromised patients, presents a challenge for scientists to develop novel, effective treatment, and prevention strategies.

Phytochemicals and Immunomodulatory Effect of Flower Extracts on Human Macrophages.

This research characterizes phytochemicals inherent in lotus flower and investigates the antioxidant and immunomodulatory activity of ethyl acetate (EA) and ethyl alcohol (ET) lotus petal extracts. In the experiment, human monocytes-derived macrophages were stimulated by lipopoly-saccharide to mimic bacteria-induced inflammation. The results showed that ferulic acid, couma-rin, and chlorogenic acid were three dominant polyphenols.

Evaluation of Anti-Inflammatory Effect of Lam. and (Less) H. Rob. Lozenges in Volunteer Smokers.

Smokers have high plaque accumulation that initiates gingival inflammation and progresses to periodontitis. Thus, oral hygiene to control microbial plaque formation is an effective method of preventing gingivitis. Medicinal plants such as Lam.

Evaluation of Mouthwash Containing DC., Lam. and A. Juss. Leaf Extracts on Dental Plaque and Gingivitis.

Oral hygiene and control of microbial plaque biofilm formation are effective methods for preventing gingivitis. Mouthwashes containing leaf extracts of the medicinal plants DC. (KL), Lam.

Phytochemical Constituents of DC. Leaves Attenuate Inflammation via NF-κB Signaling and NLRP3 Inflammasome Activity in Macrophages.

DC. (CH) is found in many countries in Southeast Asia. This plant has been reported for anti-microbial, anti-cancer and anti-inflammatory bioactivities.

Anti-Cancer Effect of 3-Hydroxy-β-Ionone Identified from Lam. Leaf on Human Squamous Cell Carcinoma 15 Cell Line.

Squamous cell carcinoma is the most common type of head and neck cancer worldwide. Radiation and chemotherapy are general treatments for patients; however, these remedies can have adverse side effects and tumours develop drug resistance. Effective treatments still require improvement for cancer patients.

Bioactive Compounds in Lam. Leaves Inhibit the Pro-Inflammatory Mediators in Lipopolysaccharide-Induced Human Monocyte-Derived Macrophages.

(MO) is an important plant for traditional medicine. The present study aimed to identify the MO active phytochemical compounds for their ability against inflamed macrophages. An ethyl acetate extract fraction of MO was fractionation by flash column chromatography.

Nosocomial infection of multidrug-resistant Acinetobacter baumannii in Thailand.

Infections caused by Acinetobacter baumannii have become a critical problem for hospital patients worldwide. We investigated the multidrug-resistant A baumannii strain that caused hospital-acquired infections in Uthai Thani Hospital, Thailand, between 2006 and 2014. In summary, the spread of a clonally related multidrug-resistant A baumannii strain was the primary cause of nosocomial infections in Uthai Thani Hospital.

Kaffir lime leaves extract inhibits biofilm formation by Streptococcus mutans.

Objectives: Although kaffir lime has been reported to exhibit antioxidant and antileukemic activity, little is known about the antimicrobial effect of kaffir lime extract. Because Streptococcus mutans has been known to cause biofilm formation, it has been considered the most important causative pathogen of dental caries. Thus, the effective control of its effects on the oral biofilm is the key to the prevention of dental caries.

Methicillin-resistant Staphylococcus aureus with reduced susceptibility to vancomycin in Sanprasitthiprasong Hospital.

Background: Staphylococcus aureus is a species of bacteria that causes a number of diseases and more than 60% of it is presently resistant to methicillin. Vancomycin is the drug of choice for the eradication of methicillin-resistant S. aureus (MRSA).

An ethyl acetate fraction of Moringa oleifera Lam. Inhibits human macrophage cytokine production induced by cigarette smoke.

Moringa oleifera Lam. (MO) has been reported to harbor anti-oxidation and anti-inflammatory activity and useful in the treatment of inflammatory diseases. However, despite these findings there has been little work done on the effects of MO on immune cellular function.