Publications by authors named "Rune Hokken"
It has recently been established that myosin, the molecular motor protein, is able to exist in two conformations in relaxed skeletal muscle. These conformations are known as the super-relaxed (SRX) and disordered-relaxed (DRX) states and are finely balanced to optimize ATP consumption and skeletal muscle metabolism. Indeed, SRX myosins are thought to have a 5- to 10-fold reduction in ATP turnover compared with DRX myosins.
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- * Strength athletes show distinct mitochondrial features, including denser cristae, smaller size, and a higher surface-to-volume ratio compared to untrained individuals, despite similar overall mitochondrial volume.
- * Resistance exercise is linked to mild mitochondrial stress and increased expression of genes involved in mitochondrial growth and stress responses, suggesting that strength training influences mitochondrial adaptations.
Aim: Glycogen particles are found in different subcellular localizations, which are utilized heterogeneously in different fibre types during endurance exercise. Although resistance exercise typically involves only a moderate use of mixed muscle glycogen, the hypothesis of the present study was that high-volume heavy-load resistance exercise would mediate a pattern of substantial glycogen depletion in specific subcellular localizations and fibre types.
Methods: 10 male elite weightlifters performed resistance exercise consisting of four sets of five (4 × 5) repetitions at 75% of 1RM back squats, 4 × 5 at 75% of 1RM deadlifts and 4 × 12 at 65% of 1RM rear foot elevated split squats.