Publications by authors named "Runbo Mao"
Article Synopsis
- Time-series experiments help us understand biological processes over time, but identifying causal mechanisms can be challenging.
- This study introduces a new algorithm that combines known biological networks with gene expression data to map out signaling pathways during the transition from aerobic to anaerobic conditions.
- The research identifies a novel regulatory network involving environmentally responsive genes that influence nitrogen metabolism regulators, ultimately affecting cell motility, enhancing our understanding of microbial physiology and its potential biotechnological applications.
Article Synopsis
- Herbal medicine Sanqi (SQ), derived from Panax notoginseng (PNS), shows promise in combating diabetes and obesity, but detailed studies on its signaling networks are limited.
- Researchers used a systems biology approach with RNA and miRNA sequencing to identify key pathways and genes related to metabolic disorders like insulin resistance.
- The study found that PNS treatment increased levels of certain protective proteins while decreasing harmful microRNAs, suggesting a mechanism for how PNS helps regulate cellular functions in metabolic issues.
