Miniaturized inertial sensor based on high-resolution dual atom interferometry.

Atom interferometry shows high sensitivity for inertial measurements in the laboratory, but it faces difficulties in field applications because of a trade-off between sensitivity and size. Therefore, there is an urgent need to develop a small sensor with high resolution for measuring acceleration and rotation in inertial navigation applications. Presented here is a miniaturized inertial sensor capable of measuring acceleration and rotation simultaneously based on high-resolution dual atom interferometers.

Self-calibrated atom-interferometer gyroscope by modulating atomic velocities.

Atom-interferometer gyroscopes have attracted much attention for their long-term stability and extremely low drift. For such high-precision instruments, self-calibration to achieve an absolute rotation measurement is critical. In this work, we propose and demonstrate the self-calibration of an atom-interferometer gyroscope.

Compact multi-channel radio frequency pulse-sequence generator with fast-switching capability for cold-atom interferometers.

Cold-atom interferometers have matured into a powerful tool for fundamental physics research, and they are currently moving from realizations in the laboratory to applications in the field. A radio frequency (RF) generator is an indispensable component of these devices for controlling lasers and manipulating atoms. In this work, we developed a compact RF generator for fast switching and sweeping the frequencies and amplitudes of atomic-interference pulse sequences.

Proteomic characteristics of PM-induced differentially expressed proteins in k-ras-silenced HBE cells.

The human bronchial epithelial cells (HBE) and K-ras-silenced HBE cells were treated with fine particulate matter (PM) samples from Taiyuan for 24 h. To screen the proteomic characteristics of PM-induced differentially expressed proteins (DEPs), the Q Exactive mass spectrometer was used. Gene ontology (GO) analysis, Kyoto encyclopedia of genes and genomes (KEGG) analysis, functional prediction, protein-protein interaction (PPI) network analysis, and visualization of differential protein interactions were performed.

Proteomic characteristics of PM -induced differentially expressed proteins in human renal tubular epithelial cells.

Human renal epithelial (HK-2) cells were treated with PM (50 μg/mL) from Shenzhen and Taiyuan, proteomics and bioinformatics were used to screen the differentially expressed proteins (DEPs). A total of 577 DEPs were screened after HK-2 cells exposed to Shenzhen PM, of which 426 were up-regulated and 151 were down-regulated. A total of 1250 DEPs were screened in HK-2 cells after exposure to Taiyuan PM, of which 488 were up-regulated and 185 were down-regulated.

Effect of c-fos gene silence on PM-induced miRNA alteration in human bronchial epithelial cells.

Human bronchial epithelial (HBE) cells and c-fos-silenced HBE cells were first exposed to fine particulate matter (PM) and the resulting miRNA sequenced. Thereafter, a weighted gene co-expression network analysis was performed using Cytoscape software to visualize the interactions between identified hub miRNAs and their target genes. Nine differentially expressed miRNAs in hub miRNAs were identified in the different treatment groups, of which miR-25-3p, miR-215-5p, and miR-145-5p were selected for further study.

Proteomic characteristics and identification of PM-induced differentially expressed proteins in hepatocytes and c-Myc silenced hepatocytes.

Proteomics and bioinformatics were applied to explore PM-induced differentially expressed proteins (DEPs) in hepatocytes (L02 cells) and c-Myc-silenced hepatocytes. L02 cells and c-Myc-silenced hepatocytes were treated with PM for 24 h. Fifty-two DEPs were screened in L02 hepatocytes, of which 28 were upregulated and 24 were downregulated.

Alteration of DNA methylation induced by PM in human bronchial epithelial cells.

This current study explored the effects of fine particulate matter (PM) on deoxyribonucleic acid methylation in human bronchial epithelial cells. Human bronchial epithelial cells were exposed to PM for 24 h after which, deoxyribonucleic acid samples were extracted, and the differences between methylation sites were detected using methylation chips. Subsequent gene ontology functional enrichment and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses were performed for the differential methylation sites.

A Novel Monitoring Navigation Method for Cold Atom Interference Gyroscope.

The implementation principle of a typical three-pulse cold atom interference gyroscope is introduced in this paper. Based on its configuration and current research status, the problems of cold atom interference gyro are pointed out. The data-rate is insufficient, and it is difficult to achieve high dynamic measurement.

Hybrid wide-band, low-phase-noise scheme for Raman lasers in atom interferometry by integrating an acousto-optic modulator and a feedback loop.

We report a hybrid scheme for phase-coherent Raman lasers with low phase noise in a wide frequency range. In this scheme, a pair of Raman lasers with a frequency difference of 3.04 GHz is generated by the ±1-order diffracted lights of an acousto-optic modulator (1.