From low remission to hope: the efficacy of targeted therapies in NUP98-R positive pediatric acute myeloid leukemia.

Background: Treating pediatric acute myeloid leukemia (AML) with NUP98 rearrangement (NUP98-R) is challenging. Standard chemotherapy results in low remission rates. This study aimed to evaluate different induction regimens and explore alternative therapies to improve outcomes.