Publications by authors named "Rumiana Tarnovska-Kadreva"
We conducted a case-control study to determine the contribution of polymorphisms in CYP2C8 (CYP2C8*3) and CYP2J2 (CYP2J2*7) to increased risk of coronary artery disease and essential hypertension in Bulgarians. The current analysis included 192 unrelated hypertensive patients, 261 patients with angiographically documented CAD (153 with myocardial infarction and 108 without myocardial infarction), and 496 population controls. The CYP2C8*3 and CYP2J2*7 polymorphisms were genotyped by TaqMan SNP Genotyping Assay.
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- Patients with poorly controlled blood pressure are at higher risk for cardiovascular issues and cognitive decline, and pulse pressure (PP) is an important but often overlooked indicator of potential damage.
- A study involving 148 patients showed significant correlations between both daytime and nighttime pulse pressure and results from cognitive tests, revealing that higher pulse pressure is linked to cognitive impairment regardless of age.
- The findings suggest that high daytime and nighttime pulse pressure can indicate not just cognitive issues but also large artery stiffness, emphasizing the need for better blood pressure management in patients of varying ages.
The role of suboptimal home-measured blood pressure control for cognitive decline.
Dement Geriatr Cogn Dis Extra
January 2012
Aim: We aim to analyze if there is any correlation between suboptimal home-/self-measured blood pressure values and the results from neuropsychological screening tests for early cognitive impairment.
Methods: We studied 325 patients with treated hypertension. Mean age was 66.