Publications by authors named "Rumeysa Taner"
Background: Dapagliflozin (DPG) is a sodium-glucose cotransporter-2 inhibitor and is used in the treatment of diabetes. In this study, we aimed to investigate the effect of DPG on cardiotoxicity caused by systemic inflammation via endoplasmic reticulum (ER) stress and autophagy.
Methods And Results: Four groups of thirty-two Wistar Albino rats were created: Control (1 ml oral physiological saline for five days and intraperitoneal saline on the 5th day), LPS (1 ml oral physiological saline for five days and intraperitoneal 5 mg/kg of LPS on the 5th day), LPS + DPG (10 mg/kg of DPG orally for five days and 5 mg/kg of LPS intraperitoneally on the 5th day), and DPG (10 mg/kg of DPG orally for five days and 5 mg/kg of SF intraperitoneally on the 5th day).
Article Synopsis
- Inflammation and oxidative stress contribute significantly to lung injury caused by cardiac ischemia, and CBD shows potential in protecting lung tissue through its antioxidant and anti-inflammatory properties.
- The study involved 40 male rats divided into four groups, where researchers induced cardiac ischemia and subsequently analyzed lung tissues for various stress and injury indicators.
- Results indicated significant lung damage in the ischemia group, but both preventive (p-CBD) and therapeutic (t-CBD) treatments with CBD effectively mitigated this damage, restoring normal levels in various tests.
Article Synopsis
- - The study investigates how systemic inflammation affects heart and aorta tissues and evaluates the potential protective effects of cannabidiol (CBD) against cardiovascular damage caused by lipopolysaccharide (LPS).
- - 32 female rats were divided into four groups to analyze the effects of LPS and CBD on heart and aorta tissues, with various tests conducted to assess tissue damage and gene expression levels after treatment.
- - Results showed that while LPS caused significant tissue damage and inflammation, CBD treatment reversed these effects, indicating its antioxidant and anti-inflammatory properties by regulating certain intracellular pathways.
Background: Doxorubicin (DOX) may cause various neurological side effects in the brain. Lercanidipine (LRD) has antioxidant, anti-inflammatory, and anti-apoptotic properties. The aim of this study was to investigate the potential benefits of.
View Article and Find Full Text PDFBackground: The blood supply of the tissue is very important in the acceleration of wound healing. Radiofrequency electromagnetic field (RF) and the pulsed magnetic field (PMF) increase vasodilation to contribute wound healing. The aim of this study was to evaluate the effects of RF and PMF on wound healing via hypoxia-inducible factor-1 alpha (Hif-1α)/endothelial nitric oxide synthase (eNOS) pathway.
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