Publications by authors named "Rumes Sriamareswaran"

Background: Inpatient delirium is common and associated with poor outcomes. Although most organisations have evidence-based guidelines to improve delirium prevention and management, delirium rates and outcomes have remained relatively unchanged over time. A lack of understanding of healthcare providers' experience of caring for people with delirium and its integration into existing guidance may explain some of the slow progress in improving delirium care.

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Background: Time to reperfusion is an important predictor of outcome in ischaemic stroke from large vessel occlusion (LVO). For patients requiring endovascular thrombectomy (EVT), the transfer times from peripheral hospitals in metropolitan and regional Victoria, Australia to comprehensive stroke centres (CSCs) have not been studied.

Aims: To determine transfer and journey times for patients with LVO stroke being transferred for consideration of EVT.

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Introduction: Iron deficiency is a common condition, especially among patients with kidney and heart failure and inflammatory bowel disease. Intravenous iron is the preferred method of treatment in these patients, but it usually requires prolonged iron polymaltose infusions or multiple administrations of alternative preparations. The aim of the study was to confirm the safety and patient acceptance of ultrarapid iron polymaltose infusions as an alternative to slower treatments and ferric carboxymaltose.

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Article Synopsis
  • The study investigated the feasibility of discharging low-risk STEMI patients early after successful primary percutaneous coronary intervention (PPCI) using the Zwolle risk score (ZRS).
  • Out of 183 participants, 132 were identified as low-risk, and those discharged within 72 hours showed no major adverse cardiovascular events (MACE) over 30 days, while also having shorter hospital stays.
  • The findings suggest that early discharge for low-risk STEMI patients post-PPCI is potentially safe, but more extensive studies are needed to confirm these results.
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  • Inflammation significantly impacts acute coronary syndromes (ACS), and colchicine, traditionally used for gout, shows promise for treating ACS due to its anti-inflammatory effects.
  • A double-blind trial with 795 patients compared colchicine treatment (0.5 mg twice daily) with a placebo, alongside standard medication, over 12 months.
  • Results indicated fewer adverse events in the colchicine group (24 vs. 38), but a higher total death rate (8 vs. 1) and more non-cardiovascular deaths, while adverse effects were similar between both groups, primarily involving gastrointestinal issues.
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Objective: Reducing time to reperfusion for ST-segment elevation myocardial infarction (STEMI) is essential in improving outcomes. Consequently, numerous strategies have been employed to reduce median door-to-balloon time (DTBT).

Methods: CODE STEMI is an ED physician-activated STEMI notification system.

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