Publications by authors named "Ruksan Buyukoglan"
Article Synopsis
- Osteogenesis imperfecta (OI) is a genetic bone disorder leading to frequent fractures, with most cases linked to specific gene mutations, predominantly inherited in an autosomal dominant manner.
- Recent studies have found a wider range of genes associated with sporadic and familial cases of OI, particularly among offspring of unaffected or consanguineous parents.
- The research highlights the importance of thorough genetic analysis, revealing not only common mutations but also rare variants linked to other conditions, aiding in the clinical diagnosis and understanding of OI's genetic complexity.
Blood component donations by apheresis have become more common in modern blood transfusion practices. We compared three apheresis instruments (Fenwal Amicus, Fresenius COM.TEC, and Trima Accel) with regard to platelet (PLT) yield, collection efficiency (CE), and collection rate (CR).
View Article and Find Full Text PDFIntroduction: We aimed to determine the frequency and microbiological causes of diarrhea occurring during the first 100 days in allogeneic (allo-) and autologous (auto-) stem cell transplantation (SCT) patients.
Methodology: A total of 452 patients who underwent transplantation due to hematological or solid organ malignancy were included. From the administration of the conditioning regimen up to day 100 post-transplant, diarrhea cases lasting at least three days with a minimum of three episodes per day were evaluated.
Objective: The aim of this study was to report the efficacy of low-density lipoprotein cholesterol (LDL-C) apheresisusing a cascade filtration system in pediatric patients with homozygous familial hypercholesterolemia (FH), and toclarify the associated adverse effects and difficulties.
Material And Methods: LDL-C apheresis using a cascade filtration system was performed in 3 pediatric patientswith homozygous FH; in total, 120 apheresis sessions were performed.
Results: Cascade filtration therapy significantly reduced the mean LDL-C values from 418 ± 62 mg/dL to 145 ± 43 mg/dL (p= 0.