Clinical spectrum of endemic leptospirosis in relation to cytokine response.

Objectives: To describe the clinical spectrum and the cytokine response of leptospirosis patients in an endemic setting of Sri Lanka.

Methods: Patients presenting to the university teaching hospital, Anuradhapura, Sri Lanka with a leptospirosis-compatible illness were recruited over a period of 12 months starting from June 2012. Daily clinical and biochemical parameters of the patients were prospectively assessed with a follow-up of 14 days after discharge.